Document Detail

Correlation between visual function, neurodevelopmental outcome, and magnetic resonance imaging findings in infants with periventricular leucomalacia.
MedLine Citation:
PMID:  10685987     Owner:  NLM     Status:  MEDLINE    
AIM: To evaluate the correlation between visual function and neurodevelopmental outcome in children with periventricular leucomalacia at 1 and 3 years. METHOD: Visual acuity, visual field, ocular motility, and optokinetic nystagmus were tested in 29 infants with periventricular leucomalacia by brain magnetic resonance imaging. All infants also had a structured neurological examination and a Griffiths developmental assessment. RESULTS: 21 of the infants showed at least one abnormality of visual function. The degree of visual impairment-that is, the number of visual tests showing abnormal results-correlated well with the results on developmental assessment at both ages. CONCLUSION: Multivariate analysis showed that visual impairment was the most important variable in determining the neurodevelopmental scores of these infants, more than their motor disability and the extent of their lesions on magnetic resonance imaging.
G Cioni; B Bertuccelli; A Boldrini; R Canapicchi; B Fazzi; A Guzzetta; E Mercuri
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Archives of disease in childhood. Fetal and neonatal edition     Volume:  82     ISSN:  1359-2998     ISO Abbreviation:  Arch. Dis. Child. Fetal Neonatal Ed.     Publication Date:  2000 Mar 
Date Detail:
Created Date:  2000-03-30     Completed Date:  2000-03-30     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  9501297     Medline TA:  Arch Dis Child Fetal Neonatal Ed     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  F134-40     Citation Subset:  AIM; IM    
Stella Maris Scientific Institute, Division of Child Neurology and Psychiatry, Via dei Giacinti 2, I-56018 Calambrone, Pisa, Italy.
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MeSH Terms
Child, Preschool
Developmental Disabilities / etiology*
Follow-Up Studies
Infant, Newborn
Leukomalacia, Periventricular / complications*
Magnetic Resonance Imaging
Multivariate Analysis
Psychomotor Disorders / etiology
Vision Disorders / complications*,  physiopathology
Visual Acuity / physiology
Visual Fields

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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