Document Detail

Correlation between vaginal stiffness index and pelvic floor disorder quality-of-life scales.
MedLine Citation:
PMID:  18217178     Owner:  NLM     Status:  MEDLINE    
The objective of this study was to determine if vaginal stiffness index, an in vivo vaginal biomechanical property, is correlated with pelvic floor disorder symptom distress, impact on quality of life, or sexual function as measured by disease-specific quality-of-life scales. Forty-eight women completed validated quality-of-life scales (pelvic floor distress inventory-short form, pelvic floor impact questionnaire, and pelvic organ prolapse/urinary incontinence sexual questionnaire) and underwent in vivo vaginal biomechanical testing. After bivariate relationships between vaginal stiffness index and demographic, obstetric, and gynecologic variables were explored, multiple linear regression controlling for pelvic organ prolapse quantitative (POP-Q) stage of prolapse was performed. The vaginal stiffness index was inversely correlated with pelvic organ prolapse distress severity (POPDI-6) after controlling for POP-Q stage of prolapse (p = 0.011, r = 0.67, r (2) = 0.450, beta = -2.3). These findings provide initial evidence for the construct validity of in vivo vaginal biomechanical testing for pelvic organ prolapse evaluation because an increasing vaginal stiffness index is correlated with decreasing symptomatic and anatomic severity of disease.
Lee B Epstein; Carol A Graham; Michael H Heit
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Validation Studies     Date:  2008-01-24
Journal Detail:
Title:  International urogynecology journal and pelvic floor dysfunction     Volume:  19     ISSN:  -     ISO Abbreviation:  Int Urogynecol J Pelvic Floor Dysfunct     Publication Date:  2008 Jul 
Date Detail:
Created Date:  2008-05-27     Completed Date:  2008-12-03     Revised Date:  2011-08-18    
Medline Journal Info:
Nlm Unique ID:  9514583     Medline TA:  Int Urogynecol J Pelvic Floor Dysfunct     Country:  England    
Other Details:
Languages:  eng     Pagination:  1013-8     Citation Subset:  IM    
Louisville Pelvic Floor Research Group, 4121 Dutchmans Lane, Suite 515, Louisville, KY 40207, USA.
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MeSH Terms
Cross-Sectional Studies
Cystocele / diagnosis*,  physiopathology
Middle Aged
Quality of Life*
Severity of Illness Index*
Uterine Prolapse / diagnosis*,  physiopathology
Vagina / physiopathology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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