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Correlation between unconjugated bilirubin and total cholesterol in the sera of 1-month-old infants.
MedLine Citation:
PMID:  20825616     Owner:  NLM     Status:  In-Process    
Abstract/OtherAbstract:
AIM: To investigate why breastfed infants are more likely to have prolonged jaundice than formula-fed infants.
METHODS: Serum unconjugated bilirubin (UCB), total cholesterol (TC) and triglyceride (TG) were measured for 102 infants of 1 month. Enrolled infants were 42 breastfed, 40 mixed-fed and 20 bottle-fed infants. Statistic analyses for relationship among UCB, TC, TG, perinatal factors and post-natal factors were performed for these infants.
RESULTS: In correlation analyses UCB was correlated with peak transcutaneous bilirubin value in neonatal period (TcBn) (r = 0.612, P < 0.0001) and with TC (r = 0.383, P < 0.0001). When analyses of covariance (ANCOVA) for UCB were performed using TcBn as the covariate, the results indicated that there was neither significant main nor interaction effect of feeding method on UCB, and that main and interaction effects of TC on UCB were significant when TC was categorised into two groups (≤150 mg/dL and >150 mg/dL).
CONCLUSIONS: It is suggested that both neonatal hyperbilirubinemia and subsequent higher plasma TC are associated factors for prolonged jaundice.
Authors:
Yoshiro Nagao; Maki Ohsawa; Tomoka Kobayashi
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Publication Detail:
Type:  Journal Article     Date:  2010-09-03
Journal Detail:
Title:  Journal of paediatrics and child health     Volume:  46     ISSN:  1440-1754     ISO Abbreviation:  J Paediatr Child Health     Publication Date:  2010 Dec 
Date Detail:
Created Date:  2010-12-20     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9005421     Medline TA:  J Paediatr Child Health     Country:  Australia    
Other Details:
Languages:  eng     Pagination:  709-13     Citation Subset:  IM    
Copyright Information:
© 2010 The Authors. Journal of Paediatrics and Child Health © 2010 Paediatrics and Child Health Division (Royal Australasian College of Physicians).
Affiliation:
Department of Pediatrics, Social Health Insurance Medical Center, Hyakunincho, Shinjuku, Tokyo, Japan. yn-nagao@pro.odn.ne.jp
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