Document Detail

Correlation between symbolic dynamics analysis indexes and neurohormonal and functional parameters in heart failure patients.
MedLine Citation:
PMID:  25160238     Owner:  NLM     Status:  In-Data-Review    
Heart failure (HF) is a cardiac disease associated with prominent alterations in the autonomic control of the cardiovascular system and high neurohormonal activation levels. Useful assessment tools may be heart rate variability (HRV) analysis and/or the study of norepinephrine (NPE) level. Nevertheless, traditional techniques of HRV analysis have proved not sufficient and the second is an invasive measurement. In this work the correlation between a parameter (kurtosis-K) computed by an emerging nonlinear technique, the symbolic dynamics analysis, and neurohormonal and functional parameters has been investigated. Results obtained show an interesting relationship between K and both ejection fraction and NPE. In particular, higher K values are associated to increasing NPE levels This finding could be useful for highlighting changes in HF patients otherwise detectable only with invasive examinations.
Mario Cesarelli; Maria Romano; Roberto Maestri; Maria Teresa La Rovere; Paolo Bifulco; Giovanni D'Addio
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Studies in health technology and informatics     Volume:  205     ISSN:  0926-9630     ISO Abbreviation:  Stud Health Technol Inform     Publication Date:  2014  
Date Detail:
Created Date:  2014-08-27     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9214582     Medline TA:  Stud Health Technol Inform     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  516-20     Citation Subset:  T    
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