| Correlation between serum phospholipid fatty acids and dietary intakes assessed a few years earlier. | |
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MedLine Citation:
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PMID: 19838922 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The fatty acid composition of serum phospholipids has been shown to reflect dietary intakes in the previous weeks or months. However, how serum phospholipids relate to fatty acid intakes over a few years has hardly been examined. We designed a cross-sectional study within the E3N cohort, the French component of the European Prospective Investigation into Cancer and Nutrition in which female participants completed a 208-item diet history questionnaire in 1993-1995 and provided blood samples in 1995-1998. The study included 1,114 women who were free of cancer at the time of blood collection. Serum phospholipid fatty acid composition was assessed by capillary gas chromatography. Partial Spearman correlations adjusted for age and body mass index showed weak to moderate, although statistically significant, positive associations between dietary and serum oleic, linoleic, arachidonic, eicosapentaenoic, and docosahexaenoic acids. Moreover, serum oleic acid was directly associated with olive oil, linoleic acid with sunflower oil, pentadecanoic acid with dairy products, long-chain n-3 fatty acids with fatty fish, and trans-monounsaturated fatty acids with manufactured foods. In conclusion, serum phospholipid pentadecanoic acid, oleic, trans-monounsaturated, and polyunsaturated fatty acids are suitable biomarkers for usual dietary intakes, although the association may weaken as the time lag between dietary assessment and blood collection increases. |
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Authors:
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Anne C M Thiébaut; Maxime Rotival; Estelle Gauthier; Gilbert M Lenoir; Marie-Christine Boutron-Ruault; Virginie Joulin; Françoise Clavel-Chapelon; Véronique Chajès |
Publication Detail:
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Type: Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Nutrition and cancer Volume: 61 ISSN: 1532-7914 ISO Abbreviation: Nutr Cancer Publication Date: 2009 |
Date Detail:
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Created Date: 2009-10-19 Completed Date: 2009-11-30 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7905040 Medline TA: Nutr Cancer Country: United States |
Other Details:
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Languages: eng Pagination: 500-9 Citation Subset: IM |
Affiliation:
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INSERM, ERI-20, Université Paris XI, EA 4045, Institut Gustave Roussy, Villejuif, France. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Aging Alcohol Drinking Biological Markers / blood Body Mass Index Case-Control Studies Cohort Studies Cross-Sectional Studies Diet* Diet Surveys Dietary Fats / administration & dosage*, analysis Energy Intake Fatty Acids / administration & dosage*, blood* Female France Humans Menopause Middle Aged Phospholipids / blood*, chemistry Questionnaires Reproducibility of Results Smoking Statistics, Nonparametric Time Factors |
| Chemical | |
Reg. No./Substance:
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0/Biological Markers; 0/Dietary Fats; 0/Fatty Acids; 0/Phospholipids |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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