Document Detail


Correlation between prenatal ultrasound and fetal autopsy findings on urinary system anomalies terminated in the second trimester.
MedLine Citation:
PMID:  24395147     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
OBJECTIVE: This prospective study was designed to compare ultrasound and autopsy findings on fetal urinary system malformations in second trimester terminations of pregnancy (TOPs) to evaluate the degree of agreement of such findings.
METHODS: From January 2003 to October 2012, a total of 308 second trimester TOPs were performed because of fetal malformation diagnosed through second trimester ultrasound examination at a tertiary referral center.
RESULT: Among 308 second trimester fetuses with congenital anomalies, 62 (20.1%) had urinary anomalies. Ultrasound and fetal autopsy findings were in full agreement for urinary system malformations in 45 (72.6 %) of 62 cases. In six (9.7 %), autopsy confirmed the malformations detected by ultrasound but showed additional lesser urinary anomalies. In 10 (16.1%) cases, autopsy revealed major urinary anomalies not determined by ultrasound. In one case (1.6%), ultrasound reported bilateral renal agenesis, however autopsy revealed a horseshoe kidney. The ultrasound screening sensitivity was 83.8%, and specificity was 99.5%.
CONCLUSION: The results showed that prenatal ultrasound achieved a high accuracy in diagnosing fetal urinary malformations. However, fetal autopsy occassionally adds valuable information to prenatal ultrasound findings. This article is protected by copyright. All rights reserved.
Authors:
Hulya Akgun; Mustafa Basbug; Mahmut Tuncay Ozgun; Figen Ozturk; Turhan Okten
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2014-1-6
Journal Detail:
Title:  Prenatal diagnosis     Volume:  -     ISSN:  1097-0223     ISO Abbreviation:  Prenat. Diagn.     Publication Date:  2014 Jan 
Date Detail:
Created Date:  2014-1-7     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8106540     Medline TA:  Prenat Diagn     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
This article is protected by copyright. All rights reserved.
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