Document Detail

Correlation between optical coherence tomography results and the Scoring Tool for Assessing Risk (STAR) score in patients with ocular hypertension.
MedLine Citation:
PMID:  20544677     Owner:  NLM     Status:  MEDLINE    
PURPOSE: To correlate retinal nerve fiber layer thickness (RNFL) and optic nerve head (ONH) parameters measured with optical coherence tomography (OCT) with the Scoring Tool for Assessing Risk (STAR) threshold in patients with ocular hypertension (OH).
METHODS: The study included 92 patients with OH. They were divided into low-risk (n=32), moderate-risk (n=36), and high-risk (n=24) groups according to STAR criteria. RNFL and ONH OCT protocols were used to evaluate all study participants. Major parameters for RNFL analysis were average RNFL thickness, superior quadrant, nasal quadrant, inferior quadrant, temporal quadrant, and segmental thickness per 12 o'clock hour position. ONH parameters were vertical integrated rim area (VIRA), horizontal integrated rim width (HIRW), disc diameter, disc area, cup area, rim area, cup-to-disc (C/D) area ratio, horizontal C/D ratio, and vertical C/D ratio.
RESULTS: The highest area under receiver operating characteristics curves for distinguishing the high-risk group from the other groups were vertical C/D ratio (0.88), C/D area (0.88), VIRA (0.87), and HIRW (0.81) for ONH parameters, and inferior (0.82) and 6 o'clock hour position (0.77) for peripapillary RNFL thickness measurements.
CONCLUSIONS: Inferior average, 6 o'clock hour position analyses for RNFL measurement, and VIRA, HIRW, C/D area, and vertical C/D ratio for ONH measurement were the best parameters for STAR staging in patients with OH.
Ilgaz Sagdic Yalvac; Destan N Kulacoglu; Banu Satana; Umit Eksioglu; Sunay Duman
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  European journal of ophthalmology     Volume:  20     ISSN:  1724-6016     ISO Abbreviation:  Eur J Ophthalmol     Publication Date:    2010 Nov-Dec
Date Detail:
Created Date:  2010-10-18     Completed Date:  2010-12-17     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9110772     Medline TA:  Eur J Ophthalmol     Country:  Italy    
Other Details:
Languages:  eng     Pagination:  1018-25     Citation Subset:  IM    
Ophthalmology Department, Medical School, Yeditepe University, Istanbul, Turkey.
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MeSH Terms
Health Status Indicators*
Intraocular Pressure
Middle Aged
Nerve Fibers / pathology*
Ocular Hypertension / diagnosis*
Optic Disk / pathology*
Optic Nerve Diseases / diagnosis*
Prospective Studies
ROC Curve
Retinal Ganglion Cells / pathology*
Risk Assessment
Risk Factors
Sensitivity and Specificity
Tomography, Optical Coherence*
Tonometry, Ocular
Visual Field Tests
Visual Fields / physiology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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