Document Detail


Correlation between one-hour, 50-g glucose screening values in successive pregnancies.
MedLine Citation:
PMID:  12170534     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: To investigate the relationship between one-hour, 50-g oral glucose screening test results in successive pregnancies and to assess the risk of gestational diabetes in women who had a previously negative glucose screening test during a prior pregnancy. STUDY DESIGN: Sixty-nine women were studied who had successive pregnancies delivered at intervals ranging from one to four years. All had glucose screening tests performed at 24-32 weeks of gestation during both pregnancies. The relationship between glucose screening test results was examined for interpregnancy intervals of up to two, three and four years. RESULTS: The correlation for interpregnancy glucose screening test results was .60, .49 and .47 for pregnancy intervals of up to two, three and four years, respectively (P < .001). The mean glucose screening test result was 108 +/- 23 mg/dL for prior pregnancies and 104 +/- 21 mg/dL for subsequent pregnancies (no significant difference). A screening test result > or = 140 mg/dL occurred in 1.6% of cases in which a previous test result was < 140 mg/dL during a prior pregnancy. CONCLUSION: A glucose screening test result of < 140 mg/dL during pregnancy is strongly predictive of a subsequent negative screening test result in a succeeding pregnancy when it occurs within four years. Under such circumstances, the risk of gestational diabetes during a subsequent pregnancy is reduced by 85-95% to no more than 0.3%.
Authors:
Gerard G Nahum; Harold Stanislaw
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Publication Detail:
Type:  Evaluation Studies; Journal Article    
Journal Detail:
Title:  The Journal of reproductive medicine     Volume:  47     ISSN:  0024-7758     ISO Abbreviation:  J Reprod Med     Publication Date:  2002 Jul 
Date Detail:
Created Date:  2002-08-12     Completed Date:  2003-01-23     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0173343     Medline TA:  J Reprod Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  564-8     Citation Subset:  IM    
Affiliation:
Department of Obstetrics and Gynecology, Duke University Medical Center-3241, Durham, NC 27710, USA. nahum001@mc.duke.edu
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MeSH Terms
Descriptor/Qualifier:
Adult
Birth Intervals
Blood Glucose
Diabetes, Gestational / blood,  diagnosis*
Female
Glucose / administration & dosage
Glucose Tolerance Test / standards*
Humans
Medical Records
Parity
Predictive Value of Tests
Pregnancy
Pregnancy Trimester, Third
Prospective Studies
Retrospective Studies
Chemical
Reg. No./Substance:
0/Blood Glucose; 50-99-7/Glucose

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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