| Correlation between neuroimaging and neurological outcome in periventricular leukomalacia: diagnostic criteria. | |
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MedLine Citation:
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PMID: 11380916 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Periventricular leukomalacia (PVL) is the most important factor in cerebral palsy in preterm infants. METHODS: In the present study, we investigated 747 preterm infants of less than 36 weeks gestation who were repeatedly examined by cranial ultrasonography and computed tomography (CT) scanning at around 40 weeks of corrected post-menstrual age. The clinical course of these infants was followed for more than 3 years and they were examined by magnetic resonance imaging (MRI) between 12 and 18 months of age. RESULTS: Single examinations in early infancy were not sufficient to diagnose PVL, but the combination of ultrasonography, CT and MRI examinations allowed the clinical diagnosis of PVL. In preterm infants, clinical PVL could be predicted from cystic PVL and periventricular echogenicity (PVE) 3 or PVE 2 prolonged over 3 weeks on ultrasonography and confirmed by MRI after 11 months of corrected age. CONCLUSIONS: We tried to determine diagnostic criteria for PVL by neuroimaging. Such criteria from neuroimaging for PVL may be useful for determining the exact occurrence rate of and clinical risk factors for PVL. |
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Authors:
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K Hashimoto; H Hasegawa; Y Kida; Y Takeuchi |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Pediatrics international : official journal of the Japan Pediatric Society Volume: 43 ISSN: 1328-8067 ISO Abbreviation: Pediatr Int Publication Date: 2001 Jun |
Date Detail:
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Created Date: 2001-05-30 Completed Date: 2001-08-30 Revised Date: 2008-05-21 |
Medline Journal Info:
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Nlm Unique ID: 100886002 Medline TA: Pediatr Int Country: Australia |
Other Details:
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Languages: eng Pagination: 240-5 Citation Subset: IM |
Affiliation:
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Division of Neonatal Medicine, Matsudo City Hospital, Matsudo, Chiba, Japan. hasikazu@hotmail.com |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Cerebral Palsy
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etiology Child, Preschool Echoencephalography Follow-Up Studies Humans Infant Infant, Newborn Infant, Premature Leukomalacia, Periventricular / complications, diagnosis* Magnetic Resonance Imaging Tomography, X-Ray Computed |
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