Document Detail

Correlation between migraine and circulating platelet aggregates.
MedLine Citation:
PMID:  4016945     Owner:  NLM     Status:  MEDLINE    
We studied platelet aggregates, by Wu and Hoak's technique, in 73 patients (49 F and 24 M), aged 14-61 (mean age 50.4 +/- 12.2) with migraine. Platelet aggregates were expressed as Platelet Aggregate Ratio (PAR). We consider as pathological PAR values lower than 86. Mean PAR value of migraine patients (78.3 +/- 8.68 SD) was significantly lower (p less than 0.001) than that of 90 control subjects (95.4 +/- 6.15 SD). Normal PAR values were found only in 27.4% of the migraine patients. The patients were divided according to the interval from the last attack: 17 patients were studied in the 1st week (PAR = 73.76 +/- 7.6 SD; 5.8% of the values in the normal range), 15 in the 2nd week (76.6 +/- 7.02 SD; 13.3% of the values in the normal range) and 41 between 15th and 30th day (80.78 +/- 8.78 SD; 29.6% of the patients in the normal range). The mean PAR value of the patients studied during the first week was significantly lower (p less than 0.01) than that of the patients studied between 15th and 30th day. No significant differences were found between the patients with classical, common and complicated migraine.
C Buttinelli; M P Lazzaro; G L Lenzi; S Paolucci; M Prencipe
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Cephalalgia : an international journal of headache     Volume:  5 Suppl 2     ISSN:  0333-1024     ISO Abbreviation:  Cephalalgia     Publication Date:  1985 May 
Date Detail:
Created Date:  1985-09-16     Completed Date:  1985-09-16     Revised Date:  2008-02-11    
Medline Journal Info:
Nlm Unique ID:  8200710     Medline TA:  Cephalalgia     Country:  NORWAY    
Other Details:
Languages:  eng     Pagination:  87-8     Citation Subset:  IM    
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MeSH Terms
Middle Aged
Migraine Disorders / blood,  physiopathology*
Platelet Aggregation*
Platelet Count

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