Document Detail


Correlation between lower urinary tract symptoms and urethral function in benign prostatic hyperplasia.
MedLine Citation:
PMID:  15382181     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
AIM: To examine the potential correlation between urethral function and lower urinary tract symptoms (LUTS) in men with benign prostatic hyperplasia (BPH). METHODS: Thirty-one patients with clinical BPH, who were confirmed to have benign prostatic enlargement (BPE) of 20 ml or more, were enrolled into the study. A mark-sheet questionnaire was used for obtaining the LUTS history. Multichannel pressure-flow urodynamic studies were performed and external urethral sphincter pressure (PEUS), intravesical pressure (PVES), and bladder neck pressure (PBN) were recorded both at maximum cystometric capacity and during voiding with 5-microtip transducers, for the purpose of detecting BPE-specific urodynamic findings at different levels within the urethra. RESULTS: There was a positive correlation between hesitancy and detrusor bladder neck dyssynergia (DBND) (P = 0.0011) and between incomplete emptying and low PBN at maximum cystometric capacity (P = 0.0425). The hesitancy proved to have no correlation with bladder neck opening time (TBNO). CONCLUSION: Urodynamic evaluation of urethral function was beneficial for attributing LUTS to clinical BPH. Among various parameters, DBND was the most specific to clinical BPH, suggesting it to be a situation where a steep rise in PBN or prostatic urethral pressure remains greater than the increasing PVES, resulting in sustained difficulty in opening the bladder neck and subsequently the subjective sensation of hesitancy.
Authors:
Hideo Nakai; Tomonori Yamanishi; Kousaku Yasuda; Satoshi Kitahara; Tsuneki Suzuki
Publication Detail:
Type:  Clinical Trial; Journal Article    
Journal Detail:
Title:  Neurourology and urodynamics     Volume:  23     ISSN:  0733-2467     ISO Abbreviation:  Neurourol. Urodyn.     Publication Date:  2004  
Date Detail:
Created Date:  2004-09-27     Completed Date:  2004-12-07     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8303326     Medline TA:  Neurourol Urodyn     Country:  United States    
Other Details:
Languages:  eng     Pagination:  618-22     Citation Subset:  IM    
Copyright Information:
2004 Wiley-Liss, Inc.
Affiliation:
Department of Urology, Dokkyo University School of Medicine, Koshigaya Hospital, Koshigaya City, Saitama, Japan. hnakai@dokkyomed.ac.jp
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MeSH Terms
Descriptor/Qualifier:
Aged
Aged, 80 and over
Electromyography
Humans
Male
Middle Aged
Prostatic Hyperplasia / complications*,  physiopathology*
Rectum / physiopathology
Transducers, Pressure
Urethra / physiopathology*
Urinary Bladder / physiopathology
Urinary Catheterization
Urinary Tract / physiopathology*
Urodynamics / physiology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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