Document Detail

Correlation between human chorionic somatomammotropin and placental weight.
MedLine Citation:
PMID:  1199703     Owner:  NLM     Status:  MEDLINE    
Human chorionic somatomammotropin concentration in serum (S-HCS) during the latter half of pregnancy was measured by radioimmunoassay and correlated to the placental weight, in two groups of normal, healthy, pregnant women. In one group, 228 samples from 47 women were examined, which gives a longitudinal series. In the other group, single samples from each of 346 pregnant women were examined, which gives a cross-sectional series. Both groups were randomized on the basis of a prospective selection. The mean values of S-HCS in each week of gestation were almost identical in the two groups, showing a steady increase until 37-38 weeks and a subsequent decrease. In the longitudinal series there was a positive correlation between the S-HCS and placental weight after 37 weeks' gestation, but not before that time. Before 37 weeks gestation the ratio S-HCS/placental weight was significantly higher with small placentae than with large placentae. This difference between small and large placentae disappeared after 37 weeks. These results point to the existence of some regulatory mechanism tending to keep the S-HCS concentration within certain limits, independent of placental weight. This mechanism appears to be lost after 37 weeks of gestation when the S-HCS concentration starts to correlate with placental weight.
J Rolschau; J Date; K Kristoffersen; G T Pedersen; M Ulrich
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Acta obstetricia et gynecologica Scandinavica     Volume:  54     ISSN:  0001-6349     ISO Abbreviation:  Acta Obstet Gynecol Scand     Publication Date:  1975  
Date Detail:
Created Date:  1976-02-27     Completed Date:  1976-02-27     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0370343     Medline TA:  Acta Obstet Gynecol Scand     Country:  SWEDEN    
Other Details:
Languages:  eng     Pagination:  341-6     Citation Subset:  IM    
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MeSH Terms
Birth Weight
Infant, Newborn
Organ Size
Placenta / anatomy & histology*
Placental Lactogen / blood*
Pregnancy Trimester, Second
Pregnancy Trimester, Third
Reg. No./Substance:
9035-54-5/Placental Lactogen

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