Document Detail

Correlation between enhancement pattern of hepatocellular carcinoma on real-time contrast-enhanced ultrasound and tumour cellular differentiation on histopathology.
MedLine Citation:
PMID:  17005515     Owner:  NLM     Status:  MEDLINE    
The objective of this study was to evaluate the correlation between the enhancement pattern of hepatocellular carcinoma (HCC) on contrast-enhanced ultrasound (CEUS) and tumour cellular differentiation on histopathology. 189 HCC lesions in 189 patients were retrospectively evaluated with CEUS and histopathological examination. CEUS was performed with SonoVue and contrast pulse sequencing. Histopathological diagnoses were made according to the Edmonson grading system. Significant differences were shown between the time that the HCC became hypoenhancing or remained echogenic in late phase and tumour cellular differentiation (p = 0.006; p = 0.036), but not with the time of commencement of hyperenhancing or commencement of isoenhancing in arterial phase and portal phase (p = 0.164, p = 0.113; p = 0.186, p = 0.070). The timing of HCC becoming hypoenhancing on CEUS is correlated with tumour cellular differentiation; well differentiated tumours wash out more slowly than poorly differentiated ones.
G-J Liu; H-X Xu; M-D Lu; X-Y Xie; Z-F Xu; Y-L Zheng; J-Y Liang
Related Documents :
1715555 - Two phase radiofrequency catheter ablation of isolated ventricular endomyocardium.
20082225 - Characterisation of focal liver lesions undetermined at grey-scale us: contrast-enhance...
9000405 - Usefulness of echo-color doppler in differentiating parathyroid lesions from other cerv...
9786115 - Contrast-enhanced endoscopic ultrasonography in gallbladder diseases.
11206615 - Approach to decortication of simple cysts and polycystic kidneys.
6607065 - Syringolymphoid hyperplasia with alopecia.
Publication Detail:
Type:  Journal Article     Date:  2006-09-27
Journal Detail:
Title:  The British journal of radiology     Volume:  80     ISSN:  1748-880X     ISO Abbreviation:  Br J Radiol     Publication Date:  2007 May 
Date Detail:
Created Date:  2007-07-19     Completed Date:  2007-09-06     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0373125     Medline TA:  Br J Radiol     Country:  England    
Other Details:
Languages:  eng     Pagination:  321-30     Citation Subset:  AIM; IM    
Department of Medical Ultrasonics, The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, People's Republic of China.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Aged, 80 and over
Carcinoma, Hepatocellular / pathology,  physiopathology,  ultrasonography*
Cell Differentiation / physiology
Image Enhancement / methods
Image Processing, Computer-Assisted / methods
Liver Neoplasms / pathology,  physiopathology,  ultrasonography*
Middle Aged
Retrospective Studies

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Variation of mesorectal volume with abdominal fat volume in patients with rectal carcinoma: assessme...
Next Document:  3D MRI in multiple sclerosis: a study of three sequences at 3 T.