| Correlation between echocardiographic left ventricular mass index and electrocardiographic variables used in left ventricular hypertrophy criteria in Chinese hypertensive patients. | |
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MedLine Citation:
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PMID: 20876051 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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INTRODUCTION: We investigated the association between echocardiographic (Echo) left ventricular mass (LVM) indexed to body surface area (LVM/BSA) or height(2.7) (LVM/H(2.7)) and electrocardiographic (ECG) variables in 546 Chinese hypertensives. METHODS: The study group was stratified by gender and by BMI into obese (BMI > or =28 kg/m(2)), overweight (BMI > or =24 kg/m(2) and BMI <28 kg/m(2)), and healthy weight (BMI <24 kg/m(2)) subgroups. Cornell voltage, Sokolow-Lyon voltage, maximum R amplitude in V(1)-V(6), Gubner-Ungerleider voltage, and the products of these amplitude variables with QRS duration were measured. RESULTS: None of the ECG and Echo values showed a statistically significant difference between the obese and overweight subgroup; thus, we used only one cut-off point of BMI at 24 kg/m(2) for stratification of the hypertensive population. Cornell voltage, Cornell product and LVM/BSA were only affected by gender in our study. For hypertensives with BMI > or =24 kg/m(2), Cornell product was correlated with LVM/BSA and LVM/H(2.7) most significantly: correlation coefficients were approximately 0.45 for males and 0.40 for females and the correlation trended to be stronger as LVM/BSA or LVM/H(2.7) increased. However, a few ECG variables showed a weak correlation with LVM/BSA or LVM/H(2.7) in the hypertensives without left ventricular hypertrophy (LVH). A low sensitivity and high specificity of ECG criteria for the detection of LVH were also derived using receiver operating characteristic curves. CONCLUSIONS: We conclude that Cornell product and Cornell voltage are the most convenient predictors for LVM/BSA with stratification only by gender. They are also the best parameters for predicting LVH in obese and overweight Chinese hypertensives, whereas estimation of LVM/BSA, LVM/H(2.7) by ECG is inaccurate in Chinese hypertensives without LVH. The cut-off point of BMI=24 kg/m(2) is suitable for stratification of body weight in further studies regarding Chinese hypertensives. |
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Authors:
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Liangdi Xie; Zili Wang |
Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Hellenic journal of cardiology : HJC = Hellēnikē kardiologikē epitheōrēsē Volume: 51 ISSN: 1109-9666 ISO Abbreviation: Hellenic J Cardiol Publication Date: 2010 Sep-Oct |
Date Detail:
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Created Date: 2010-09-29 Completed Date: 2011-01-20 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101257381 Medline TA: Hellenic J Cardiol Country: Greece |
Other Details:
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Languages: eng Pagination: 391-401 Citation Subset: IM |
Affiliation:
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Fujian Hypertension Research Institute, The First Affiliated Hospital of Fujian Medical University, Academy of Integrative Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou City, PR China. ldxie@hotmail.com |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Aged, 80 and over Area Under Curve Body Height Body Surface Area Comorbidity Electrocardiography Female Heart Ventricles / ultrasonography* Humans Hypertension / epidemiology, ultrasonography* Hypertrophy, Left Ventricular / diagnosis* Male Middle Aged Obesity / epidemiology ROC Curve Retrospective Studies Risk Assessment / methods Young Adult |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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