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Correlation between the characteristics of acceleration and visco elasticity of artery wall under pulsatile flow conditions (physical meaning of I* as a parameter of progressive behaviors of atherosclerosis and arteriosclerosis).
MedLine Citation:
PMID:  23442239     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Previously, I* parameter has been proposed to diagnose noninvasively the progressive degree of atherosclerosis which is considered to concern the discrimination of the progressive degree of visco elasticity of blood vessel wall. However, the detailed physical meaning of this parameter has not yet been clarified. In this paper, the theoretical analysis and experiments were conducted and the detailed physical meaning of I* parameter was clarified. The following results were obtained. I* parameter was found to well correlate with the progressive degree of visco elasticity of blood vessel wall characterized by the Ith* parameter derived based on the analysis of visco elasticity in this paper. That is, I* was found to have the physical meaning of representing the progressive degree of visco elasticity of blood vessel wall. On the basis of this results, using clinical data, two dimensional representation between the progressive degree of visco elasticity of blood vessel wall by I* and the decrease in the rigidity of blood vessel wall by PWV was found to be useful to conduct much more detailed diagnosis of atherosclerosis.
Authors:
A Toshimitsu Yokobori; Toshihito Ohmi; Ryouhei Monma; Yuki Tomono; Kyousuke Inoue; Michiaki Owa; Masataka Ichiki; Noriko Mochizuki; Hidetoshi Yamashita
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Bio-medical materials and engineering     Volume:  23     ISSN:  1878-3619     ISO Abbreviation:  Biomed Mater Eng     Publication Date:  2013 Jan 
Date Detail:
Created Date:  2013-02-27     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9104021     Medline TA:  Biomed Mater Eng     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  75-91     Citation Subset:  IM    
Affiliation:
Faculty of Graduate School of Engineering, Tohoku University, Sendai, Japan.
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