| Correlation between cerebral blood flow values obtained by Xenon/CT and Kety-Schmidt (N2O) methods. | |
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MedLine Citation:
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PMID: 8686435 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The means of the cerebral blood flow (CBF) values obtained by the stable xenon enhanced CT (Xe/CT) method using two different CT scanners were compared with global CBF value obtained by the Kety-Schmidt (N2O) method as a reference. Xe/CT CBF values were obtained using a GE CT9200 (31 patients, 2 flow maps, 120 kV, absorption constant of 0.040) as well as a GE ProSeed Accell (38 patients, 4 flow maps, 80 kV, absorption constant of 0.028). The protocol of inhalation in the Xe/XT method consisted of 4 min wash-in and 4-min wash-out of 35% stable xenon. In the Kety-Schmidt method, 15% N2O gas was inhaled for 10 min. The N2O content of blood samples was measured using a van Slyke-Neill blood gas analyzer. We corrected all obtained CBF values for a PaCO2 of 34 mmHG (CBF34). The global CBF34 values obtained by the Kety-Schmidt method were linearly correlated with the CBF34 values obtained using the CT9200 and with those obtained using the ProSeed Accell, and the regression line equations were, respectively, Y = 0.64X + 13.7 (X: CT9200, Y: Kety-Schmidt, r = 0.666, p < 0.01) and Y = 0.99X + 11.2 (X: ProSeed Accell, Y: Kety Schmidt, r = 0.756, p < 0.01). Since the CBF values obtained by the Xe/CT method using different CT scanners are not always the same as the global CBF values obtained by the Kety-Schmidt method, CBF values obtained by the Xe/CT method should be corrected referring to the regression line obtained by applying both methods for each patient. |
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Authors:
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O Tone; U Ito; H Tomita; H Akimoto; H Sakemi |
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Publication Detail:
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Type: Comparative Study; Journal Article |
Journal Detail:
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Title: Acta neurologica Scandinavica. Supplementum Volume: 166 ISSN: 0065-1427 ISO Abbreviation: Acta Neurol. Scand., Suppl.c Publication Date: 1996 |
Date Detail:
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Created Date: 1996-08-22 Completed Date: 1996-08-22 Revised Date: 2012-05-07 |
Medline Journal Info:
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Nlm Unique ID: 0370337 Medline TA: Acta Neurol Scand Suppl Country: DENMARK |
Other Details:
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Languages: eng Pagination: 18-21 Citation Subset: IM |
Affiliation:
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Department of Neurosurgery, Musashino Red Cross Hospital, Tokyo Japan. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Blood Flow Velocity / physiology Brain / blood supply* Brain Injuries / physiopathology, radionuclide imaging* Cerebrovascular Disorders / physiopathology, radionuclide imaging* Female Humans Male Middle Aged Nitrous Oxide / diagnostic use* Regional Blood Flow / physiology Sensitivity and Specificity Subarachnoid Hemorrhage / physiopathology, radionuclide imaging* Tomography, X-Ray Computed / instrumentation* Xenon Radioisotopes / diagnostic use* |
| Chemical | |
Reg. No./Substance:
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0/Xenon Radioisotopes; 10024-97-2/Nitrous Oxide |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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