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Correlation between breast arterial calcification detected on mammography and cerebral artery disease.
MedLine Citation:
PMID:  21046130     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
PURPOSE: This study was carried out to determine the relationship between breast arterial calcification (BAC) and cerebral artery disease.
MATERIALS AND METHODS: We investigated the relationship between BAC on mammography and cerebral artery-origin T2-hyperintensity on brain MRI and which is associated with an increased risk for stroke. A total of 168 women, ages 40-78 years, who underwent both mammography and brain MRI, were enrolled in this study. BAC was counted as positive if it was found on more than one view a breast. The T2-hyperintensity was systemically defined and graded as follows: punctuate; patchy; and confluent white-matter hyperintensity (WMH); caps; bands; and irregular periventricular hyperintensity (PVH). Patchy and confluent WMH and irregular PVH were considered as positive findings for cerebral artery disease. We also obtained data regarding cardiovascular risk factors that might function as confounding factors. Statistical analysis was performed for association of the BAC and positive MRI findings.
RESULT: The presence of BAC showed a strong correlation with the positive MRI findings (Odds ratios, adjusted with statically significant cardiovascular factors of 6.86 for positive WMH and 9.04 for positive PVH, p < 0.05).
CONCLUSION: The mammographic finding of BAC, which may be a useful marker of women at higher risk for stroke, should receive more of clinicians' attention and its presence should never be omitted from the report.
Authors:
Kook Jin Ahn; Young Joo Kim; Hang Joo Cho; Hyeon Woo Yim; Bong Joo Kang; Sung Hun Kim; Hyun Suk Kim; Ki Tae Kim; Jae Hee Lee; In Yong Whang
Publication Detail:
Type:  Journal Article     Date:  2010-11-03
Journal Detail:
Title:  Archives of gynecology and obstetrics     Volume:  284     ISSN:  1432-0711     ISO Abbreviation:  Arch. Gynecol. Obstet.     Publication Date:  2011 Oct 
Date Detail:
Created Date:  2011-09-13     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8710213     Medline TA:  Arch Gynecol Obstet     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  957-64     Citation Subset:  IM    
Affiliation:
Department of Radiology, College of Medicine, Uijeongbu St. Mary's Hospital, The Catholic University of Korea, CPO Box, Kyunggido, 480-717, Korea.
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