Document Detail

Correlation between biomagnetic and Doppler findings of the uterine artery in normal and preeclamptic pregnancies.
MedLine Citation:
PMID:  15662694     Owner:  NLM     Status:  MEDLINE    
OBJECTIVES: To elucidate the hemodynamics of the uterine artery in normal and abnormal pregnancies by use of Doppler ultrasound and SQUID biomagnetometry. METHOD: Two hundred and three women (gestational age 28-42 weeks) were included in the study. Forty-three of them had preeclampsia and/or intrauterine growth restriction and 160 were normal. Uterine artery waveform measurements were evaluated by use of pulsatility index (PI) (normal value PI<1.45). Biomagnetic signals of uterine arteries were recorded and analyzed with Fourier analysis. The biomagnetic signals were distributed according to spectral amplitudes as high (140-300 fT/ radicalHz), low (50-110 fT/ radicalHz) and borderline (111-139 fT/ radicalHz). RESULTS: There was a statistically significant difference between normal and abnormal pregnancies concerning the waveform amplitudes (p < 0.001) and the PI index (p < 0.001). Specifically, we noticed high biomagnetic amplitudes in most normal pregnancies (92.5%) and low biomagnetic amplitudes in most preeclamptic cases (90.7%). CONCLUSIONS: Our study results indicated that biomagnetic measurements of uterine artery might prove to be useful in the evaluation of the fetal well being, especially in cases of preeclampsia and intrauterine growth restriction.
P Anastasiadis; K Avgidou; A N Anastasiadis; A Kotini; N Koutlaki; P Anninos
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Publication Detail:
Type:  Comparative Study; Journal Article; Validation Studies    
Journal Detail:
Title:  Prenatal diagnosis     Volume:  25     ISSN:  0197-3851     ISO Abbreviation:  Prenat. Diagn.     Publication Date:  2005 Jan 
Date Detail:
Created Date:  2005-01-31     Completed Date:  2005-04-26     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  8106540     Medline TA:  Prenat Diagn     Country:  England    
Other Details:
Languages:  eng     Pagination:  51-6     Citation Subset:  IM    
Copyright Information:
Copyright (c) 2005 John Wiley & Sons, Ltd.
Department of Obstetrics and Gynecology, Medical School, Democritus University of Thrace, University Campus, Alexandroupolis, Greece.
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MeSH Terms
Blood Flow Velocity / physiology
Electromagnetic Phenomena* / instrumentation,  methods
Fetal Growth Retardation / diagnosis,  physiopathology,  ultrasonography
Gestational Age
Pre-Eclampsia / diagnosis*,  physiopathology,  ultrasonography
Pregnancy, High-Risk
Ultrasonography, Doppler / methods*
Ultrasonography, Prenatal / methods*
Uterus / blood supply*

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