Document Detail


Correlation between anal manometry and endosonography in females with faecal incontinence.
MedLine Citation:
PMID:  17956588     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: Female faecal incontinence (FI) is largely because of sphincter injury at childbirth. Sphincter assessment aims to identify surgically correctable defects. We aimed to identify endoanal ultrasonography (EAUS) parameters that correlate with sphincter function. METHOD: One hundred females with FI and 28 healthy asymptomatic females were prospectively assessed. Wexner FI score was recorded and all subjects underwent anorectal manometry and EAUS. Multiple EAUS parameters were assessed and correlated with external (EAS) and internal (IAS) anal sphincter function, determined by maximum squeeze pressure (MSP) and maximum resting pressure (MRP) respectively. Parameters included sphincter quality (echogenicity), thickness, perineal body thickness (PBT) and defect characteristics (angle, length). Results are expressed as medians and interquartile range (IQR). RESULTS: Median Wexner score was 14 (12-17). Maximum EAS thickness significantly correlated with MSP (P = 0.019). EAS defects were detected in 84 patients and seven controls (P < 0.0001). Full-length EAS defects were only detected in FI group and had significantly lower MSP [MSP mmHg: full length 85 (65-103) vs partial length 119 (75-155), P = 0.006]. FI patients were more likely to have a mixed echogenicity of EAS compared with controls. EAS ring quality, PBT and defect angle were not significant. IAS quality was significantly associated with MRP [MRP mmHg: uniform 62 (43-82) vs mixed 47 (30.5-57.5), P = 0.002]. CONCLUSION: Certain EAUS parameters can be predictive of anal sphincter function. These include the presence of an EAS defect and its length, EAS maximum thickness, IAS ring quality. Integration of these parameters can give better EAUS correlation with manometry for FI evaluation.
Authors:
M A Titi; J T Jenkins; A Urie; R G Molloy
Related Documents :
9011448 - Effect of octreotide on sphincter of oddi motility in patients with acute recurrent pan...
3235478 - Manometric study of the activity of alizapride on the motor function of the human sphin...
1500658 - Uninhibited anal sphincter relaxation syndrome. a new syndrome with report of four cases.
16344058 - The role of transsphincteric pressure and proximal gastric volume in acid reflux before...
2197008 - Intraoperative anaphylaxis to latex.
9011448 - Effect of octreotide on sphincter of oddi motility in patients with acute recurrent pan...
Publication Detail:
Type:  Journal Article     Date:  2007-10-23
Journal Detail:
Title:  Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland     Volume:  10     ISSN:  1463-1318     ISO Abbreviation:  Colorectal Dis     Publication Date:  2008 Feb 
Date Detail:
Created Date:  2008-01-17     Completed Date:  2008-02-21     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100883611     Medline TA:  Colorectal Dis     Country:  England    
Other Details:
Languages:  eng     Pagination:  131-7     Citation Subset:  IM    
Affiliation:
Department of Surgical Gastroenterology, Gartnavel General Hospital, Glasgow, UK. mohtiti@yahoo.com
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Case-Control Studies
Chi-Square Distribution
Endosonography*
Fecal Incontinence / physiopathology*,  ultrasonography*
Female
Humans
Manometry
Middle Aged
Prospective Studies
Risk Factors
Statistics, Nonparametric

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  The NHS Bowel Cancer Screening Programme--a realistic approach with additional benefits.
Next Document:  Apoptotic pathway induced by transduction of RUNX3 in the human gastric carcinoma cell line MKN-1.