| Correlation between QT dispersion and burn severity. | |
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MedLine Citation:
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PMID: 12163289 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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QT dispersion, defined as the maximal-minus-minimal QT interval on a 12-lead electrocardiogram, has emerged as a non-invasive measurement for quantifying the spatial inhomogeneity of ventricular repolarization under various conditions, including acute stress. Because burn injuries elicit acute stress reactions, it was hypothesized that QT dispersion increases with the severity of the burn injury. To test the hypothesis, 13 burned patients (age range of 22-76 years, nine males, ranging from 4.0 to 75.0% of total body surface area burned) in whom a measurable 12-lead electrocardiogram had been obtained within 4h after arrival at the emergency department were identified retrospectively, and their QTc intervals, i.e. QT intervals corrected for heart rate by the standard Bazett formula, were measured. QTc dispersion (QTcd) was then calculated, and correlations were assessed with burn severity (burn index, BI; prognostic burn index, PBI). Of the 13 patients, nine patients had a prolonged QTcd (>40 ms), and linear correlation analyses showed significant positive correlations between QTcd and both BI and PBI (r=0.61 and 0.62, respectively). In conclusion, QT dispersion was greater in the burned patients, and although the pathophysiology was unclear from the present study, the findings suggested that acute stress contributed to the spatial inhomogeneity of ventricular repolarization. |
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Authors:
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Masaru Suzuki; Katsunori Aoki; Kazuhiko Sekine; Naoki Aikawa |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Burns : journal of the International Society for Burn Injuries Volume: 28 ISSN: 0305-4179 ISO Abbreviation: Burns Publication Date: 2002 Aug |
Date Detail:
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Created Date: 2002-08-06 Completed Date: 2002-11-06 Revised Date: 2008-11-21 |
Medline Journal Info:
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Nlm Unique ID: 8913178 Medline TA: Burns Country: England |
Other Details:
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Languages: eng Pagination: 481-5 Citation Subset: IM |
Affiliation:
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Department of Emergency and Critical Care Medicine, School of Medicine, Keio University, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan. suzuki@sc.itc.keio.ac.jp |
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Burns / complications*, physiopathology* Electrocardiography* Female Heart Rate / physiology Humans Male Middle Aged Outcome Assessment (Health Care) Predictive Value of Tests Reproducibility of Results Retrospective Studies Stress, Physiological / etiology*, physiopathology* Trauma Severity Indices |
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