Document Detail

Correlation between pre-operative brain magnetic resonance angiography findings and intra-operative cerebral oxygen saturation during coronary artery bypass graft surgery.
MedLine Citation:
PMID:  20146875     Owner:  NLM     Status:  MEDLINE    
Coronary artery bypass graft (CABG) patients often have cerebrovascular disease and pre-operative brain magnetic resonance angiography (MRA) frequently reveals cerebral vasculature stenosis. This study was designed to investigate whether pre-operative MRA findings correlated with regional cerebral oxygen saturation (ScO(2)) in 120 patients undergoing on-pump or off-pump CABG. Following MRA examination, patients were divided into six groups of 20 patients each based on MRA findings (no stenosis, mild stenosis or severe stenosis) and procedure (on-pump or off-pump CABG). Mean ScO(2) values over 3 min were determined at seven periods during surgery. Patients with severe cerebrovascular stenosis showed significantly lower ScO(2) than other groups during off-pump CABG. During on-pump CABG, ScO(2) decreased significantly during cardiopulmonary bypass in all groups and was significantly lower in the severe stenosis group. Pre-operative MRA and intra-operative ScO(2) monitoring may help to identify patients at increased risk of brain damage during or following CABG.
Y-J Roh; J-W Choi; J-H Suh; J-Y Shim; I-C Choi
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Journal of international medical research     Volume:  37     ISSN:  0300-0605     ISO Abbreviation:  J. Int. Med. Res.     Publication Date:    2009 Nov-Dec
Date Detail:
Created Date:  2010-02-11     Completed Date:  2010-03-24     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0346411     Medline TA:  J Int Med Res     Country:  England    
Other Details:
Languages:  eng     Pagination:  1772-9     Citation Subset:  IM    
Department of Anaesthesiology, College of Medicine, Seoul National University, Seoul, Republic of Korea.
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MeSH Terms
Brain / metabolism*,  radiography*
Coronary Artery Bypass*
Intraoperative Period
Magnetic Resonance Angiography*
Middle Aged
Oxygen / metabolism*
Preoperative Period*
Reg. No./Substance:

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