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Correlation between Ischaemia-modified Albumin and Intermediate-density Lipoprotein in Haemodialysis Patients with End-stage Renal Disease.
MedLine Citation:
PMID:  21986159     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
This study investigated the association between ischaemia-modified albumin (IMA), a biomarker of cardiac ischaemia, and increases in the levels of intermediatedensity lipoprotein (IDL), an atherogenic particle that can cause oxidative stress, in haemodialysis patients with end-stage renal disease (ESRD). Fasting levels of serum IMA and lipids/lipoproteins were analysed in 15 patients and 15 healthy control subjects. There was a close positive correlation between IMA and IDL levels in ESRD patients but no significant correlation between IMA and lipids/lipoproteins in control subjects. This suggests a possible link between the characteristic dyslipoproteinaemia found in ESRD and levels of IMA and, if confirmed in studies with larger sample sizes, may lead to further studies on the potential of the relationship between IMA and IDL as a biomarker in haemodialysis patients with ESRD.
Authors:
K Kotani; S Kimura; E Kinugasa; H Ogata; R Caccavello; N Taniguchi; A Gugliucci
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Journal of international medical research     Volume:  39     ISSN:  1473-2300     ISO Abbreviation:  J. Int. Med. Res.     Publication Date:  2011  
Date Detail:
Created Date:  2011-10-11     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0346411     Medline TA:  J Int Med Res     Country:  England    
Other Details:
Languages:  eng     Pagination:  1541-5     Citation Subset:  IM    
Affiliation:
Department of Clinical Laboratory Medicine, Jichi Medical University, 3311-1 Yakushiji, Shimotsuke-City, Tochigi 329-0498, Japan; Glycation, Oxidation and Disease Laboratory, Touro University-California, Vallejo, CA, USA. kazukotani@jichi.ac.jp.
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