| Correlation between Ischaemia-modified Albumin and Intermediate-density Lipoprotein in Haemodialysis Patients with End-stage Renal Disease. | |
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MedLine Citation:
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PMID: 21986159 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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This study investigated the association between ischaemia-modified albumin (IMA), a biomarker of cardiac ischaemia, and increases in the levels of intermediatedensity lipoprotein (IDL), an atherogenic particle that can cause oxidative stress, in haemodialysis patients with end-stage renal disease (ESRD). Fasting levels of serum IMA and lipids/lipoproteins were analysed in 15 patients and 15 healthy control subjects. There was a close positive correlation between IMA and IDL levels in ESRD patients but no significant correlation between IMA and lipids/lipoproteins in control subjects. This suggests a possible link between the characteristic dyslipoproteinaemia found in ESRD and levels of IMA and, if confirmed in studies with larger sample sizes, may lead to further studies on the potential of the relationship between IMA and IDL as a biomarker in haemodialysis patients with ESRD. |
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Authors:
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K Kotani; S Kimura; E Kinugasa; H Ogata; R Caccavello; N Taniguchi; A Gugliucci |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The Journal of international medical research Volume: 39 ISSN: 1473-2300 ISO Abbreviation: J. Int. Med. Res. Publication Date: 2011 |
Date Detail:
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Created Date: 2011-10-11 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0346411 Medline TA: J Int Med Res Country: England |
Other Details:
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Languages: eng Pagination: 1541-5 Citation Subset: IM |
Affiliation:
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Department of Clinical Laboratory Medicine, Jichi Medical University, 3311-1 Yakushiji, Shimotsuke-City, Tochigi 329-0498, Japan; Glycation, Oxidation and Disease Laboratory, Touro University-California, Vallejo, CA, USA. kazukotani@jichi.ac.jp. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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