Document Detail

Correlation between 2,3-diphosphoglycerate and red cell mass in the third trimester of pregnancy.
MedLine Citation:
PMID:  4024878     Owner:  NLM     Status:  MEDLINE    
In 30 non-anemic, and in 7 non-thalassemic, anemic pregnant women the red cell mass (RCM) was determined at 32-36 weeks of pregnancy, using isotopes, and was correlated with red cell 2,3-DPG, using the method of Keitt. The increase in 2,3-DPG in pregnant women with low RCM was in the same range as in those with increased RCM. Thus, 2,3-DPG can not be used to diagnose a RCM deficit in pregnancy. The relationship between 2,3-DPG and RCM in the third trimester was complex: in the 7 anemic women there was an inverse relationship, which failed to reach statistical significance, probably because of the small number of cases; in the 30 non-anemic women there was a significant, positive correlation between 2,3-DPG and RCM. The cause of this positive relationship needs further investigation.
C H Tsai; N K de Leeuw
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Acta obstetricia et gynecologica Scandinavica     Volume:  64     ISSN:  0001-6349     ISO Abbreviation:  Acta Obstet Gynecol Scand     Publication Date:  1985  
Date Detail:
Created Date:  1985-09-09     Completed Date:  1985-09-09     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0370343     Medline TA:  Acta Obstet Gynecol Scand     Country:  SWEDEN    
Other Details:
Languages:  eng     Pagination:  303-5     Citation Subset:  IM    
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MeSH Terms
Anemia / blood*
Diphosphoglyceric Acids / blood*
Erythrocyte Volume*
Pregnancy Complications, Hematologic / blood*
Pregnancy Trimester, Third
Reg. No./Substance:
0/Diphosphoglyceric Acids; 138-81-8/2,3-Diphosphoglycerate

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