Document Detail


Correlation between [18f]fluorodeoxyglucose positron-emission tomography scan and histology of pelvic nodes in early-stage cervical cancer.
MedLine Citation:
PMID:  20393032     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: The histological results of pelvic lymphadenectomy were studied in patients treated for early-stage cervical cancer (<4 cm) who had no nodal uptake on [(18)F]fluorodeoxyglucose positron-emission tomography combined with integrated computed tomography (FDG-PET/CT). PATIENTS AND METHODS: Patients treated between 2005 and 2008 for stage IB1 cervical cancer cancer <4 cm who underwent a FDG-PET/CT followed by surgical evaluation of pelvic nodes were reviewed. RESULTS: A total of 16 patients were studied. The median age of patients was 43 (range 29-62) years. Surgery was performed laparoscopically and by laparotomic approach in 13 and 3 cases, respectively. Two patients had histologically proven pelvic involvement. The false-negative rate and negative predictive value of PET-CT imaging for pelvic nodal involvement were 13% and 87%, respectively. CONCLUSION: The accuracy of PET-CT imaging in predicting the pelvic nodal status is very low in patients with early-stage cervical cancer and is not able to replace lymphadenectomy.
Authors:
Enrica Bentivegna; Catherine Uzan; Sebastien Gouy; Sophie Leboulleux; Pierre Duvillard; Jean Lumbroso; Christine Haie-Meder; Martin Schlumberger; Philippe Morice
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Anticancer research     Volume:  30     ISSN:  1791-7530     ISO Abbreviation:  Anticancer Res.     Publication Date:  2010 Mar 
Date Detail:
Created Date:  2010-04-15     Completed Date:  2010-05-18     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8102988     Medline TA:  Anticancer Res     Country:  Greece    
Other Details:
Languages:  eng     Pagination:  1029-32     Citation Subset:  IM    
Affiliation:
Department of surgery, Gustave Roussy Institute University Paris Sud, 39 rue Camille Desmoulins, 94805 Villejuif Cedex, France.
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MeSH Terms
Descriptor/Qualifier:
Adult
Female
Fluorodeoxyglucose F18 / diagnostic use*,  pharmacokinetics
Humans
Lymph Node Excision
Lymph Nodes / metabolism,  pathology,  radionuclide imaging*,  surgery
Lymphatic Metastasis
Middle Aged
Neoplasm Staging
Positron-Emission Tomography / methods
Radiopharmaceuticals / diagnostic use*,  pharmacokinetics
Uterine Cervical Neoplasms / metabolism,  pathology,  radionuclide imaging*,  surgery
Chemical
Reg. No./Substance:
0/Radiopharmaceuticals; 63503-12-8/Fluorodeoxyglucose F18

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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