| Correlation of amniotic fluid optical density at 650 nm and lecithin/sphingomyelin ratios with phosphatidylglycerol. | |
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MedLine Citation:
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PMID: 6465225 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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In this study we have attempted to correlate amniotic fluid optical density measurements and lecithin/sphingomyelin (L/S) ratios with the presence of phosphatidylglycerol. An 85% correlation (126 of 148) of all three parameters was noted. When the assumption was made that phosphatidylglycerol is indicative of fetal pulmonary maturity, 93 of 94 fluid samples having an optical density at 650 nm greater than or equal to 0.15 had demonstrable phosphatidylglycerol for a 1% false positive rate. In 53 fluid samples having an optical density at 650 nm less than 0.15, phosphatidylglycerol was present in 11 and absent in 42, a 21% false negative rate. The same analyses with lecithin/sphingomyelin ratios showed a 5% false positive rate and a 31% false negative rate. |
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Authors:
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A J Sbarra; C L Cetrulo; B Paul; R Selvaraj; G Thomas; R Kennison |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: American journal of obstetrics and gynecology Volume: 149 ISSN: 0002-9378 ISO Abbreviation: Am. J. Obstet. Gynecol. Publication Date: 1984 Aug |
Date Detail:
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Created Date: 1984-08-31 Completed Date: 1984-08-31 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0370476 Medline TA: Am J Obstet Gynecol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 740-3 Citation Subset: AIM; IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Amniotic Fluid
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analysis* Centrifugation Densitometry / methods Diagnostic Errors Female Fetal Organ Maturity Humans Lung / embryology* Phosphatidylcholines / analysis* Phosphatidylglycerols / analysis* Pregnancy Spectrophotometry Sphingomyelins / analysis* |
| Chemical | |
Reg. No./Substance:
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0/Phosphatidylcholines; 0/Phosphatidylglycerols; 0/Sphingomyelins |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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