Document Detail

Correlation of amniotic fluid optical density at 650 nm and lecithin/sphingomyelin ratios with phosphatidylglycerol.
MedLine Citation:
PMID:  6465225     Owner:  NLM     Status:  MEDLINE    
In this study we have attempted to correlate amniotic fluid optical density measurements and lecithin/sphingomyelin (L/S) ratios with the presence of phosphatidylglycerol. An 85% correlation (126 of 148) of all three parameters was noted. When the assumption was made that phosphatidylglycerol is indicative of fetal pulmonary maturity, 93 of 94 fluid samples having an optical density at 650 nm greater than or equal to 0.15 had demonstrable phosphatidylglycerol for a 1% false positive rate. In 53 fluid samples having an optical density at 650 nm less than 0.15, phosphatidylglycerol was present in 11 and absent in 42, a 21% false negative rate. The same analyses with lecithin/sphingomyelin ratios showed a 5% false positive rate and a 31% false negative rate.
A J Sbarra; C L Cetrulo; B Paul; R Selvaraj; G Thomas; R Kennison
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  American journal of obstetrics and gynecology     Volume:  149     ISSN:  0002-9378     ISO Abbreviation:  Am. J. Obstet. Gynecol.     Publication Date:  1984 Aug 
Date Detail:
Created Date:  1984-08-31     Completed Date:  1984-08-31     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0370476     Medline TA:  Am J Obstet Gynecol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  740-3     Citation Subset:  AIM; IM    
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MeSH Terms
Amniotic Fluid / analysis*
Densitometry / methods
Diagnostic Errors
Fetal Organ Maturity
Lung / embryology*
Phosphatidylcholines / analysis*
Phosphatidylglycerols / analysis*
Sphingomyelins / analysis*
Reg. No./Substance:
0/Phosphatidylcholines; 0/Phosphatidylglycerols; 0/Sphingomyelins

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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