Document Detail


Correlation of amniotic fluid optical density at 650 nm and lecithin/sphingomyelin ratios with phosphatidylglycerol.
MedLine Citation:
PMID:  6465225     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
In this study we have attempted to correlate amniotic fluid optical density measurements and lecithin/sphingomyelin (L/S) ratios with the presence of phosphatidylglycerol. An 85% correlation (126 of 148) of all three parameters was noted. When the assumption was made that phosphatidylglycerol is indicative of fetal pulmonary maturity, 93 of 94 fluid samples having an optical density at 650 nm greater than or equal to 0.15 had demonstrable phosphatidylglycerol for a 1% false positive rate. In 53 fluid samples having an optical density at 650 nm less than 0.15, phosphatidylglycerol was present in 11 and absent in 42, a 21% false negative rate. The same analyses with lecithin/sphingomyelin ratios showed a 5% false positive rate and a 31% false negative rate.
Authors:
A J Sbarra; C L Cetrulo; B Paul; R Selvaraj; G Thomas; R Kennison
Related Documents :
1682185 - The use of amniotic fluid viscosity measurements to establish fetal lung maturity.
15061315 - The effect of clinical characteristics on the lecithin/sphingomyelin ratio and lamellar...
402075 - Effect of betamethasone on analysis of amniotic fluid in the rhesus-sensitized pregnancy.
17671165 - Melanosome maturation defect in rab38-deficient retinal pigment epithelium results in i...
7326375 - The relationship of maternal prenatal development to progress in labor and fetal-newbor...
3792905 - Growth of the fetal sheep small intestine.
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  American journal of obstetrics and gynecology     Volume:  149     ISSN:  0002-9378     ISO Abbreviation:  Am. J. Obstet. Gynecol.     Publication Date:  1984 Aug 
Date Detail:
Created Date:  1984-08-31     Completed Date:  1984-08-31     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0370476     Medline TA:  Am J Obstet Gynecol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  740-3     Citation Subset:  AIM; IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Amniotic Fluid / analysis*
Centrifugation
Densitometry / methods
Diagnostic Errors
Female
Fetal Organ Maturity
Humans
Lung / embryology*
Phosphatidylcholines / analysis*
Phosphatidylglycerols / analysis*
Pregnancy
Spectrophotometry
Sphingomyelins / analysis*
Chemical
Reg. No./Substance:
0/Phosphatidylcholines; 0/Phosphatidylglycerols; 0/Sphingomyelins

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  The difference between the systolic time intervals of the left and right ventricles during fetal lif...
Next Document:  Sonographic determination of fetal sex from twelve weeks of gestation.