Document Detail


Correlation of alpha-1-antitrypsin (PI) polymorphism between blood and semen.
MedLine Citation:
PMID:  7783389     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The correlation between isoprotein types of alpha-1-antitrypsin (PI) in blood and semen samples from the same individual was determined in 48 Japanese men by the combined technique of isoelectric focusing with immobilized pH gradients and immunoblotting. Five common PI types (M1, M1M2, M1M3, M2 and M2M3) were detected in the blood plasma samples. However, PI-specific bands in semen migrated more cathodally than those in plasma into a pI region of approximately 5.05, and about 17% of the semen samples could not be phenotyped: the rest were easily phenotyped and their PI types were found to correlate with the type found in the corresponding blood samples. PI typing could therefore provide an additional discriminant characteristic for the forensic examination of individualization from semen samples.
Authors:
K Sawazaki; H Takeshita; E Tenjo; D Nadano; T Yasuda; R Iida; K Kishi
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Nihon hōigaku zasshi = The Japanese journal of legal medicine     Volume:  49     ISSN:  0047-1887     ISO Abbreviation:  Nihon Hoigaku Zasshi     Publication Date:  1995 Apr 
Date Detail:
Created Date:  1995-07-19     Completed Date:  1995-07-19     Revised Date:  2006-09-04    
Medline Journal Info:
Nlm Unique ID:  0413715     Medline TA:  Nihon Hoigaku Zasshi     Country:  JAPAN    
Other Details:
Languages:  eng     Pagination:  65-9     Citation Subset:  IM    
Affiliation:
Department of Legal Medicine, Fukui Medical School, Japan.
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MeSH Terms
Descriptor/Qualifier:
Forensic Medicine*
Humans
Hydrogen-Ion Concentration
Immunoblotting
Isoelectric Focusing
Male
Polymorphism, Genetic*
Semen / enzymology*
alpha 1-Antitrypsin / classification,  genetics*
Chemical
Reg. No./Substance:
0/alpha 1-Antitrypsin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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