Document Detail

Correlation of Rheological Parameters in Maternal and Foetal Blood at Term.
MedLine Citation:
PMID:  25000448     Owner:  NLM     Status:  Publisher    
Abstract Objective: An association between maternal and fetal blood rheology has not yet been investigated nor is it known whether and to what extend fetal blood rheology may be affected by maternal conditions. Methods: At delivery, blood was drawn from the cubital vein of 4,985 consecutive mothers and from the umbilical cord during birth for determination of blood rheological parameters (Erythrocyteaggregation stasis [E0], low shear [E1], Plasmaviscosity [Pv]) in addition to Hemoglobin values [Hb] and Hematocrit [Hct]. Results: Maternal and newborn Pv (r = 0.2, p < 0.0001) correlated statistically significant. There was a remarkable correlation between fetal Pv and gestational age (r = 0.197; p < 0.001). Iron supplementation during pregnancy led to increased fetal Hb, Hct as well as E0 and E1 (p<0.0001), did not have a significant impact on neonatal Pv (p = 0.068). Smoking mothers gave birth to neonates with significantly higher Pv (p=0.049), E0 (p=0.016) and E1 (p=0.013). Conclusions: The increase of foetal plasmaviscosity at advanced delivery time-points refers to a more gaining protein synthesis by the foetal liver and thus maturity of the foetus. Iron supplementation as well as smoking during pregnancy is associated with a relative hyper viscosity in the foetus at delivery.
Roland Csorba; Amr A Soliman; Christian Wieg; Panagiotis Tsikouras; Werner Rath; Georg-Friedrich von Tempelhoff
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2014-7-7
Journal Detail:
Title:  The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians     Volume:  -     ISSN:  1476-4954     ISO Abbreviation:  J. Matern. Fetal. Neonatal. Med.     Publication Date:  2014 Jul 
Date Detail:
Created Date:  2014-7-7     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101136916     Medline TA:  J Matern Fetal Neonatal Med     Country:  -    
Other Details:
Languages:  ENG     Pagination:  1-30     Citation Subset:  -    
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