Document Detail

Correlation of Mini-Mental-State-Examination (MMSE), Syndrom-Kurztest (SKT) and Clock test (CT) scores in patients with cognitive impairment assessed by means of multiple regression and response surface analysis.
MedLine Citation:
PMID:  15531019     Owner:  NLM     Status:  MEDLINE    
The objective of our study was to assess the correlation of routine neuropsychological test results in elderly patients referred to a gerontopsychiatric ward. MMSEs, CTs and SKTs were performed in 94 patients (age: median = 74 years, range = 54-89 years; 64 f, 30 m) with mild to moderate dementia and evaluated retrospectively. Pairwise Spearman rank correlation, multiple regression and response surface analysis were used to assess relations between test results. The scores of all three tests used were reciprocally correlated (P < 0.05) yielding the following pairwise R-values: SKT versus MMSE: -0.77, SKT versus CT: 0.69, MMSE versus Clock test: -0.61. Multiple regression analysis showed a maximum correlation of 0.87 and marked standardised beta values, if SKT was chosen as dependent variable. Test scores could be well fitted to both symmetric linear (SKT = a + b x CT + c x MMSE; R(2) = 0.67, P < 0.01) and non-linear (SKT = a + b x CT + c x MMSE + d x CT(2) + e x MMSE(2) + f x CT x MMSE; R(2) = 0.67, P < 0.01) response surfaces. In conclusion, test scores of SKT, CT or MMSE in patients with dementia showed a marked correlation. In clinical practice the may be considered as almost interchangeable test options.
Horst J Koch; Klaus Gürtler; Alexander Szecsey
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Archives of gerontology and geriatrics     Volume:  40     ISSN:  0167-4943     ISO Abbreviation:  Arch Gerontol Geriatr     Publication Date:    2005 Jan-Feb
Date Detail:
Created Date:  2004-11-08     Completed Date:  2005-05-05     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8214379     Medline TA:  Arch Gerontol Geriatr     Country:  Ireland    
Other Details:
Languages:  eng     Pagination:  7-14     Citation Subset:  IM    
Department of Gerontopsychiatry, University Clinic of Psychiatry, Universitätsstrasse 84, D-93053 Regensburg, Germany.
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MeSH Terms
Aged, 80 and over
Cognition Disorders / diagnosis*
Geriatric Assessment
Middle Aged
Neuropsychological Tests / statistics & numerical data*
Regression Analysis
Retrospective Studies
Statistics, Nonparametric

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