| Correlation between serum and plasma antibody titers to mycobacterial antigens. | |
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MedLine Citation:
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PMID: 21047999 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The ability to utilize serum or plasma samples interchangeably is useful for tuberculosis (TB) serology. We demonstrate a strong correlation between antibody titers to several mycobacterial antigens in serum versus plasma from HIV-infected and non-HIV-infected TB and non-TB patients (r = 0.99 to 0.89; P < 0.0001). Plasma and serum can be used interchangeably in the same antibody detection assays. |
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Authors:
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Michael Siev; Xian Yu; Rafael Prados-Rosales; Frank T Martiniuk; Arturo Casadevall; Jacqueline M Achkar |
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Publication Detail:
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Type: Evaluation Studies; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't Date: 2010-11-03 |
Journal Detail:
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Title: Clinical and vaccine immunology : CVI Volume: 18 ISSN: 1556-679X ISO Abbreviation: Clin. Vaccine Immunol. Publication Date: 2011 Jan |
Date Detail:
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Created Date: 2011-01-05 Completed Date: 2011-04-21 Revised Date: 2011-08-01 |
Medline Journal Info:
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Nlm Unique ID: 101252125 Medline TA: Clin Vaccine Immunol Country: United States |
Other Details:
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Languages: eng Pagination: 173-5 Citation Subset: IM |
Affiliation:
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Graduate Division of Biomedical Sciences, Albert Einstein College of Medicine, Bronx, NY 10461, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Antibodies, Bacterial / blood* Antigens, Bacterial / immunology* Bacterial Proteins / immunology Female HIV Infections / complications, immunology Humans Malate Synthase / immunology Male Mannans / immunology Middle Aged Mycobacterium bovis / immunology* Mycobacterium tuberculosis / immunology* Plasma / immunology* Serum / immunology* Tuberculosis / complications, immunology |
| Grant Support | |
ID/Acronym/Agency:
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1UL1RR029893/RR/NCRR NIH HHS; AI-033146/AI/NIAID NIH HHS; AI-033774/AI/NIAID NIH HHS; AI-052733/AI/NIAID NIH HHS; AI-067665/AI/NIAID NIH HHS; AI-51519/AI/NIAID NIH HHS; HL-059842/HL/NHLBI NIH HHS; K23 AI067665-05/AI/NIAID NIH HHS; //Howard Hughes Medical Institute |
| Chemical | |
Reg. No./Substance:
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0/Antibodies, Bacterial; 0/Antigens, Bacterial; 0/Bacterial Proteins; 0/MPT51 protein, Mycobacterium; 0/Mannans; 53026-40-7/arabinomannan; EC 2.3.3.9/Malate Synthase |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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