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The Correlation Between Retinal Blood Flow Velocity Measured by the Retinal Function Imager and Various Physiological Parameters.
MedLine Citation:
PMID:  22882006     Owner:  NLM     Status:  Publisher    
BACKGROUND AND OBJECTIVE:The Retinal Function Imager (RFI) (Optical Imaging Ltd., Rehovot, Israel) measures retinal blood flow velocity non-invasively. The authors studied the reproducibility of these measurements and assessed the effect of physiological components on them. PATIENTS AND METHODS:Sixty-seven individuals with no retinal pathology were recruited. Velocity reproducibility was verified by comparing repeated RFI measurements. The correlation of the velocity with physiological parameters was assessed by mixed linear and Gaussian models. RESULTS:The average velocity was 4.2 ± 0.9 mm/sec arterial and 3.3 ± 0.8 mm/sec venous. Variability was 7.5% ± 3.7% and interclass correlation coefficient was r = 0.744. Venous velocity decreased after 40 years of age (0.32 mm/sec per decade, P < .01). Arterial velocity increased as mean arterial pressure increased (0.25 mm/sec per 10 mm Hg, P < .01). There was also a positive association between velocities and heart rate (arteries: 0.21 mm/sec per 10 bpm, P < .05; veins: 0.22 mm/sec per 10 bpm, P < .01). CONCLUSION:The RFI provides a reproducible, non-invasive technique to assess retinal velocities.
Zvia Burgansky-Eliash; Anat Lowenstein; Meira Neuderfer; Anat Kesler; Hila Barash; Darin A Nelson; Amiram Grinvald; Adiel Barak
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-8-10
Journal Detail:
Title:  Ophthalmic surgery, lasers & imaging : the official journal of the International Society for Imaging in the Eye     Volume:  -     ISSN:  1938-2375     ISO Abbreviation:  Ophthalmic Surg Lasers Imaging     Publication Date:  2012 Aug 
Date Detail:
Created Date:  2012-8-13     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101155780     Medline TA:  Ophthalmic Surg Lasers Imaging     Country:  -    
Other Details:
Languages:  ENG     Pagination:  1-8     Citation Subset:  -    
Copyright Information:
Copyright 2012, SLACK Incorporated.
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