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A Correlation Between Fractional Anisotropy Variations and Clinical Recovery in Spinal Cord Infarctions.
MedLine Citation:
PMID:  22211992     Owner:  NLM     Status:  Publisher    
PURPOSE: To describe diffusion-weighted imaging and diffusion tensor imaging variations in spinal cord infarctions. METHODS: We studied the apparent diffusion coefficient (ADC) and fractional anisotropy (FA) local variations in 2 patients with spinal cord infarcts in the conus region at days 3-4, 9-10, and 15-22 after clinical onset, and correlated them with the clinical outcome. RESULTS: Both patients (19 and 53 years-old) presented spinal cord infarction unraveled by paraparesis and bladder dysfunction. Although initial clinical and radiological presentations were similar, the first patient early and fully recovered whereas the second kept severe bladder dysfunctions. Early absolute values of FA and ADC did not seem to correlate with outcome. At day 9-10, the second patient, who presented definitive sequel, had decreasing values of FA in the ischemic region whereas they had increased in the first patient, who fully recovered. CONCLUSION: FA values could be an interesting prognosis marker in spinal cord ischemia, which needs to be confirmed by a larger study. J Neuroimaging 2011;XX:1-3.
Marie Théaudin; Guillaume Saliou; Christian Denier; David Adams; Denis Ducreux
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-12-30
Journal Detail:
Title:  Journal of neuroimaging : official journal of the American Society of Neuroimaging     Volume:  -     ISSN:  1552-6569     ISO Abbreviation:  -     Publication Date:  2011 Dec 
Date Detail:
Created Date:  2012-1-3     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9102705     Medline TA:  J Neuroimaging     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
© 2011 by the American Society of Neuroimaging.
From the AP-HP, Hôpital Bicêtre, Service de Neurologie, Le Kremlin-Bicêtre, France (MT, CD); UMR788 INSERM, 94275, Le Kremlin Bicêtre Cedex, France (MT, DA, DD); and AP-HP, Hôpital Bicêtre, Service de Neuroradiologie, Le Kremlin-Bicêtre, France (GS, DD).
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