Document Detail


Correlation between the degree of air trapping in chest HRCT and cardiopulmonary exercise test parameters: could HRCT be a predictor of disease severity?
MedLine Citation:
PMID:  21361713     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: The purpose of this study was to examine whether the degree of air trapping in high resolution computed tomography (HRCT) of patients with histories of sulfur mustard gas exposure during suspended full expiration correlated with various parameters of the cardiopulmonary exercise test as the gold standard for assessment of pulmonary function.
METHODS: In this analytic study 75 male patients, each with a history of sulfur mustard gas exposure, were investigated. Each participant underwent an incremental cardiopulmonary exercise test, pulmonary function test and arterial oxygen saturation for hemoglobin measurement. For HRCT examination, both lungs were divided into three parts (upper, middle, and lower) and in each part images were separately observed from the involved area point of view (<25% ≤6/24; >25% ≥6/24).
RESULTS: A total of 49.3% of the patients (37/75) had evidence of air trapping in over 25% of their lung segments. The mean age±SD in the patients with air trapping of =25% or <25% were 41.1±6.8 and 39.7±4.0 years, respectively (P=0.281). In our study there was no significant difference in pulmonary function test findings (FEV1, FVC and FEV1/FVC) between the two groups. There was no significant correlation with air trapping of =25% and any of the exercise test parameters. Also, no correlation was found between significant air trapping and exercise test findings in maximum exercise and anaerobic situations.
CONCLUSIONS: No correlation was found between HRCT and cardiopulmonary exercise test findings. HRCT is neither pathognomic of the disease nor a good predictor of disease severity but it might be suggestive of mustard lung injuries.
Authors:
Mostafa Ghanei; Mohsen Sheyacy; Mohammad Amin Abbasi; Alireza Ani; Jafar Aslani
Related Documents :
10899063 - Isometric handgrip training reduces arterial pressure at rest without changes in sympat...
14767243 - The 24-h urinary cortisol/cortisone ratio for monitoring training in elite swimmers.
24641963 - Comparison of frequency of significant electrocardiographic abnormalities in endurance ...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Archives of Iranian medicine     Volume:  14     ISSN:  1735-3947     ISO Abbreviation:  Arch Iran Med     Publication Date:  2011 Mar 
Date Detail:
Created Date:  2011-03-02     Completed Date:  2011-07-22     Revised Date:  2013-05-15    
Medline Journal Info:
Nlm Unique ID:  100889644     Medline TA:  Arch Iran Med     Country:  Iran    
Other Details:
Languages:  eng     Pagination:  86-90     Citation Subset:  IM    
Affiliation:
Chemical Injuries Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran. m.ghanei@bmsu.ac.ir
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adult
Air
Chemical Warfare Agents / adverse effects
Chronic Disease
Exercise Test
Exhalation
Humans
Lung Diseases / chemically induced,  physiopathology,  radiography*
Male
Middle Aged
Mustard Gas / adverse effects
Respiratory Function Tests*
Severity of Illness Index*
Tomography, X-Ray Computed*
Chemical
Reg. No./Substance:
0/Chemical Warfare Agents; 505-60-2/Mustard Gas
Comments/Corrections
Comment In:
Arch Iran Med. 2011 Mar;14(2):84-5   [PMID:  21361712 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Improving the therapeutic window of retinal photocoagulation by spatial and temporal modulation of t...
Next Document:  Adverse reactions following immunization with MMR vaccine in children at selected provinces of Iran.