| Correlation between blood pressure responses to dietary sodium and potassium intervention in a Chinese population. | |
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MedLine Citation:
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PMID: 19763120 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Blood pressure (BP) responses to dietary sodium and potassium intake vary among individuals. We examined the correlation between BP responses to dietary low-sodium, high-sodium, and potassium supplementation interventions in a feeding study. METHODS: A total of 1,906 Chinese aged > or = 16 years participated in the dietary intervention that included a 7-day low-salt intervention (51.3 mmol/day), a 7-day high-salt intervention (307.8 mmol/day), and a 7-day high-salt plus potassium supplementation (60 mmol/day) intervention. BP was measured nine times during the 3-day baseline observation and during the last 3 days of each intervention phase using a random-zero sphygmomanometer. RESULTS: The correlation coefficients (95% confidence intervals (CIs)) of the BP responses to low-sodium and high-sodium interventions were -0.47 (-0.51 to -0.44), -0.47 (-0.50 to -0.43), and -0.45 (-0.49 to -0.42) for systolic BP (SBP), diastolic BP (DBP), and mean arterial pressure (MAP), respectively (all P < 0.0001). The correlation coefficients (95% CI) of the BP responses to high-sodium intervention and potassium supplementation were -0.52 (-0.56 to -0.49), -0.48 (-0.52 to 0.45), and -0.52 (-0.55 to -0.48) for SBP, DBP, and MAP, respectively (all P < 0.0001). The kappa coefficients were moderate, varying from 0.28 to 0.34, between BP responses to low-sodium and high-sodium interventions (all P < 0.0001). CONCLUSIONS: These results indicate there is a moderate correlation between BP responses to low-sodium and to high-sodium interventions, and BP responses to high-sodium intervention and potassium supplementation. Furthermore, our study suggests that individuals who were more sensitive to high-sodium diet might benefit more from a low-sodium and/or high-potassium intervention aimed at lowering BP levels. |
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Authors:
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Qi Zhao; Dongfeng Gu; Jing Chen; Lydia A Bazzano; Dabeeru C Rao; James E Hixson; Cashell E Jaquish; Jie Cao; Jichun Chen; Jianxin Li; Treva Rice; Jiang He |
Publication Detail:
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Type: Clinical Trial; Journal Article; Multicenter Study; Research Support, N.I.H., Extramural Date: 2009-09-17 |
Journal Detail:
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Title: American journal of hypertension Volume: 22 ISSN: 1941-7225 ISO Abbreviation: Am. J. Hypertens. Publication Date: 2009 Dec |
Date Detail:
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Created Date: 2009-11-20 Completed Date: 2010-01-25 Revised Date: 2011-06-30 |
Medline Journal Info:
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Nlm Unique ID: 8803676 Medline TA: Am J Hypertens Country: United States |
Other Details:
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Languages: eng Pagination: 1281-6 Citation Subset: IM |
Affiliation:
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Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, Louisiana, USA. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Asian Continental Ancestry Group
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genetics Blood Pressure / drug effects* China Humans Potassium, Dietary / administration & dosage, pharmacology* Sodium, Dietary / administration & dosage, pharmacology* |
| Grant Support | |
ID/Acronym/Agency:
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K08HL091108/HL/NHLBI NIH HHS; R01 HL087263-04/HL/NHLBI NIH HHS; R01 HL090682-03/HL/NHLBI NIH HHS; R01HL087263/HL/NHLBI NIH HHS; R01HL090682/HL/NHLBI NIH HHS; U01 HL072507-06/HL/NHLBI NIH HHS; U01HL072507/HL/NHLBI NIH HHS |
| Chemical | |
Reg. No./Substance:
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0/Potassium, Dietary; 0/Sodium, Dietary |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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