Document Detail

Correlation of akinesia with graft patency and cardiac enzyme after off-pump coronary artery bypass graft surgery.
MedLine Citation:
PMID:  20595777     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: The aim of the present study was to identify the clinical implications of newly developed akinesia in echocardiography after off-pump coronary artery bypass graft (CABG) surgery and its relationship with graft patency.
METHODS AND RESULTS: A total of 512 patients underwent off-pump CABG from January 2007 to November 2008. Two hundred and thirty-nine patients, whose echocardiography and multi-slice computed tomography data were available, were included in the study. Wall motion was subdivided into 16 segments and analyzed. Patients were separated into group A with newly developed akinesia (n=20), and group B without newly developed akinesia (n=219). Morbidity and early mortality, cardiac enzyme level, and graft patency were compared. The incidence of newly developed akinesia according to the anatomical territory was as follows: anterior, 5; lateral, 3; posterior, 7; and multiple territories, 5. Significant differences in preoperative ejection fraction were observed between the 2 groups (group A, 45.0+/-7%; group B, 58.0+/-12.2%, P<0.001). There was no statistical difference in the mean number of bypassed grafts and the complete revascularization rate. Complication and early mortality rates were insignificant between the 2 groups. There was little association between graft patency, cardiac enzyme level, and newly developed akinesia (P>0.05). Multivariate analysis showed that the preoperative ejection fraction was a risk factor for newly developed akinesia.
CONCLUSIONS: The mechanism of development of akinesia after off-pump CABG might be attributable to intraoperative coronary malperfusion, which is probably due to cardiac manipulation rather than graft occlusion.
Hongseok Yang; Young-Nam Youn; Kyung Jong Yoo
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Publication Detail:
Type:  Journal Article     Date:  2010-06-29
Journal Detail:
Title:  Circulation journal : official journal of the Japanese Circulation Society     Volume:  74     ISSN:  1347-4820     ISO Abbreviation:  Circ. J.     Publication Date:  2010 Aug 
Date Detail:
Created Date:  2010-07-30     Completed Date:  2010-12-06     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101137683     Medline TA:  Circ J     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  1564-9     Citation Subset:  IM    
Department of Thoracic and Cardiovascular Surgery, Yonsei Cardiovascular Hospital, Yonsei University Health System, Yonsei University Medical College, Seoul, South Korea.
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MeSH Terms
Coronary Artery Bypass, Off-Pump / adverse effects*
Enzymes / analysis
Hypokinesia / etiology*
Middle Aged
Myocardium / enzymology*
Risk Factors
Stroke Volume
Vascular Grafting / adverse effects*
Vascular Patency
Reg. No./Substance:

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