Document Detail

Correlates of lateral ventricular size in chronic schizophrenia, II: biological measures.
MedLine Citation:
PMID:  2428259     Owner:  NLM     Status:  MEDLINE    
CSF homovanillic acid levels showed a significant negative correlation with ventricle-brain ratios (VBRs) in a group of drug-free chronic schizophrenic male veterans, while CSF 5-hydroxyindoleacetic acid levels showed a similar, nearly significant trend. The response of plasma human growth hormone to 0.75 mg of apomorphine also demonstrated a significant negative correlation with VBR in this group, but other measures of central neurotransmitter activity were unrelated to ventricular size.
M F Losonczy; I S Song; R C Mohs; A A Mathé; M Davidson; B M Davis; K L Davis
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, Non-P.H.S.    
Journal Detail:
Title:  The American journal of psychiatry     Volume:  143     ISSN:  0002-953X     ISO Abbreviation:  Am J Psychiatry     Publication Date:  1986 Sep 
Date Detail:
Created Date:  1986-09-29     Completed Date:  1986-09-29     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0370512     Medline TA:  Am J Psychiatry     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1113-8     Citation Subset:  AIM; IM    
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MeSH Terms
Apomorphine / pharmacology
Brain / anatomy & histology*
Cerebral Ventricles / anatomy & histology*
Chronic Disease
Growth Hormone / blood,  secretion
Homovanillic Acid / cerebrospinal fluid
Hydroxyindoleacetic Acid / cerebrospinal fluid
Schizophrenia / diagnosis*
Secretory Rate / drug effects
Reg. No./Substance:
306-08-1/Homovanillic Acid; 54-16-0/Hydroxyindoleacetic Acid; 58-00-4/Apomorphine; 9002-72-6/Growth Hormone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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