Document Detail

Correction for variations in MRI scanner sensitivity in brain studies with histogram matching.
MedLine Citation:
PMID:  9469718     Owner:  NLM     Status:  MEDLINE    
Quantitative comparisons of abnormalities in MRI scans between patients or within patients serially are affected by variations in MR scanner performance. A histogram matching method is proposed to correct for variation in scanner sensitivity. It is demonstrated that this histogram matching method reduced the variation in white matter intensities across normal subjects from 7.5 to 2.5% and provided a method to remove the threshold dependency in lesion volume measurement with global thresholding in patients with multiple sclerosis (MS). The effectiveness of the method was compared with three other possible correction schemes. The histogram matching method was shown to be 2 to 5 times better.
L Wang; H M Lai; G J Barker; D H Miller; P S Tofts
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine     Volume:  39     ISSN:  0740-3194     ISO Abbreviation:  Magn Reson Med     Publication Date:  1998 Feb 
Date Detail:
Created Date:  1998-03-24     Completed Date:  1998-03-24     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8505245     Medline TA:  Magn Reson Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  322-7     Citation Subset:  IM    
Institute of Neurology, London, United Kingdom.
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MeSH Terms
Brain / anatomy & histology*,  pathology
Case-Control Studies
Image Processing, Computer-Assisted / methods
Magnetic Resonance Imaging / methods*
Multiple Sclerosis / pathology*
Reproducibility of Results

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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