Document Detail


Correction of anaemia and thrombocytopenia in a case of adult type I osteopetrosis with recombinant human erythropoietin (rHuEPO).
MedLine Citation:
PMID:  7772533     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A case of adult osteopetrosis Type I was diagnosed in a 22-year-old female. She presented for investigation of anaemia with 'myelophthisic' characteristics and extramedullary haemopoiesis which was resistant to haematinics, nandrolone and low-dose corticosteroids. She became progressively transfusion-dependent with gradually worsening thrombocytopenia. She was successfully treated with recombinant erythropoietin. Anaemia as well as thrombocytopenia were corrected. There appeared to be a synergistic action of erythropoietin with steroids.
Authors:
J Meletis; M Samarkos; E Michali; S Vavourakis; C Meletis; C Poziopoulos; N Stavrogianni; K Konstantopoulos; G Vaiopoulos; X Yataganas
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  British journal of haematology     Volume:  89     ISSN:  0007-1048     ISO Abbreviation:  Br. J. Haematol.     Publication Date:  1995 Apr 
Date Detail:
Created Date:  1995-07-13     Completed Date:  1995-07-13     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0372544     Medline TA:  Br J Haematol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  911-3     Citation Subset:  IM    
Affiliation:
First Department of Internal Medicine,University of Athens School of Medicine, Laikon General Hospital, Greece.
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MeSH Terms
Descriptor/Qualifier:
Adult
Anemia / etiology,  therapy*
Bone Marrow Diseases / complications,  therapy
Erythropoietin / therapeutic use*
Female
Humans
Osteopetrosis / therapy*
Recombinant Proteins / therapeutic use
Thrombocytopenia / etiology,  therapy*
Chemical
Reg. No./Substance:
0/Recombinant Proteins; 11096-26-7/Erythropoietin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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