| Correction of hyperkalemia in dogs with chronic kidney disease consuming commercial renal therapeutic diets by a potassium-reduced home-prepared diet. | |
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MedLine Citation:
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PMID: 20337915 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Hyperkalemia occurs in dogs with chronic kidney disease (CKD). Objectives: (1) To determine the incidence of hyperkalemia in dogs with CKD, (2) to determine the proportion of hyperkalemic dogs that required modification of dietary potassium intake, (3) to evaluate the response to dietary modification. METHODS: The hospital database was reviewed retrospectively to identify dogs with CKD and persistent (>5.3 mmol/L on at least 3 occasions) or severe (K > or = 6.5 mmol/L) hyperkalemia while consuming a therapeutic renal diet. Records of dogs with hyperkalemia that were prescribed a home-prepared, potassium-reduced diet were evaluated further. Response was evaluated by changes in body weight, BCS, and serum potassium concentration. RESULTS: One hundred and fifty-two dogs were diagnosed with CKD, of which 47% had > or =1 documented episode of hyperkalemia, 25% had > or = 3 episodes of hyperkalemia, and 16% had > or =1 episodes of severe hyperkalemia (K > 6.5 mmol/L). Twenty-six dogs (17.2%) with CKD and hyperkalemia were prescribed a potassium-reduced, home-prepared diet. The potassium concentration of all hyperkalemic dogs on therapeutic diets (potassium content, 1.6 +/- 0.23 g/1,000 kcal of metabolizable energy [ME]) was 6.5 +/- 0.5 mmol/L but decreased significantly to 5.1 +/- 0.5 mmol/L in 18 dogs available for follow-up in response to the dietary modification (0.91 +/- 0.14 g/1,000 kcal of ME, P < .001). Potassium concentration normalized in all but 1 dog. CONCLUSIONS AND CLINICAL IMPORTANCE: Hyperkalemia is a potential complication of CKD. In a subset of CKD dogs, hyperkalemia can be associated with commercial renal diets and could restrict use of these diets. Appropriately formulated, potassium-reduced, diets are an effective alternative to correct hyperkalemia. |
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Authors:
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G Segev; A J Fascetti; L P Weeth; L D Cowgill |
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Publication Detail:
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Type: Journal Article Date: 2010-03-19 |
Journal Detail:
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Title: Journal of veterinary internal medicine / American College of Veterinary Internal Medicine Volume: 24 ISSN: 0891-6640 ISO Abbreviation: J. Vet. Intern. Med. Publication Date: 2010 May-Jun |
Date Detail:
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Created Date: 2010-06-22 Completed Date: 2010-08-31 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8708660 Medline TA: J Vet Intern Med Country: United States |
Other Details:
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Languages: eng Pagination: 546-50 Citation Subset: IM |
Affiliation:
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Veterinary Teaching Hospital, University of California, Davis, CA, USA. gsegev@agri.huji.ac.il |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animal Feed
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analysis* Animals Diet / veterinary* Dogs Hyperkalemia / diet therapy, etiology, veterinary* Kidney Failure, Chronic / complications, diet therapy, veterinary* Potassium / chemistry* |
| Chemical | |
Reg. No./Substance:
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7440-09-7/Potassium |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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