Document Detail

Coronary vasospasm as a potential cause of myocardial infarction and paroxysmal atrial fibrillation in a relatively young woman.
MedLine Citation:
PMID:  1914277     Owner:  NLM     Status:  MEDLINE    
Vasospasm-related myocardial infarction in young women with normal coronary arteries has infrequently been reported and vasospasm-related paroxysmal atrial fibrillation (PAF) has rarely been described. We present a 33-year-old woman with old inferior myocardial infarction and postinfarction angina at rest; the angina was accompanied by PAF and electrocardiographic ST-segment elevation in the inferior leads. Coronary angiography revealed normal coronary arteries and intracoronary acetylcholine provoked an intense and diffuse spasm of the right and left coronary artery. The spasm of the right coronary artery was associated with PAF and ST-segment elevation in the inferior leads. Frequently documented PAF, accompanied by chest discomfort and ST-segment elevation in the inferior leads, was more effectively removed with isosorbide dinitrate than with disopyramide. These data suggest that coronary vasospasm is a likely cause of myocardial infarction and even PAF, although the precise mechanism leading to PAF remains unknown.
M Horimoto; K Igarashi; T Takenaka; T Anbo
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Clinical cardiology     Volume:  14     ISSN:  0160-9289     ISO Abbreviation:  Clin Cardiol     Publication Date:  1991 Aug 
Date Detail:
Created Date:  1991-11-05     Completed Date:  1991-11-05     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7903272     Medline TA:  Clin Cardiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  699-702     Citation Subset:  IM    
Division of Cardiology, National Sapporo Hospital, Japan.
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MeSH Terms
Acetylcholine / diagnostic use
Atrial Fibrillation / diagnosis,  etiology*
Coronary Angiography
Coronary Vasospasm / complications*,  diagnosis,  radiography
Myocardial Infarction / diagnosis,  etiology*
Reg. No./Substance:

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