Document Detail

Coronary thrombosis related to use of Xenadrine RFA.
MedLine Citation:
PMID:  15902827     Owner:  NLM     Status:  MEDLINE    
Recently, ephedra was removed from the U.S. marketplace due to a heightened concern that dietary supplements containing ephedra may present "an unreasonable risk of illness or injury." This is the 1st time the U.S. Food and Drug Administration has banned an herbal supplement, and the ban sheds light on the potential harm of nutritional supplements that are used for weight loss or as a boost to athletic performance. We report the case of a body builder who used Xenadrine RFA, an ephedra-containing supplement, at recommended doses for nearly a year; he then experienced an acute myocardial infarction, which was documented to be secondary to thrombosis in situ. We ruled out other possible causes of myocardial infarction, as well a hypercoagulable state. There was no evidence of illicit drug use. Our report serves as a poignant reminder of the potential dangers of herbal supplementation, especially when used to heighten athletic performance.
Rajesh Sachdeva; Satish Sivasankaran; Robert F Fishman; Stuart W Zarich; Craig A McPherson
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Texas Heart Institute journal / from the Texas Heart Institute of St. Luke's Episcopal Hospital, Texas Children's Hospital     Volume:  32     ISSN:  0730-2347     ISO Abbreviation:  Tex Heart Inst J     Publication Date:  2005  
Date Detail:
Created Date:  2005-05-20     Completed Date:  2005-09-22     Revised Date:  2013-04-18    
Medline Journal Info:
Nlm Unique ID:  8214622     Medline TA:  Tex Heart Inst J     Country:  United States    
Other Details:
Languages:  eng     Pagination:  74-7     Citation Subset:  IM    
Division of Cardiology, Department of Medicine, Bridgeport Hospital, Yale Universitty School of Medicine, Bridgeport, Connecticut 06610, USA.
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MeSH Terms
Coronary Thrombosis / chemically induced*
Dietary Supplements / adverse effects*
Ephedra / adverse effects*
Myocardial Infarction / chemically induced*
Plant Preparations / adverse effects*
Reg. No./Substance:
0/Plant Preparations

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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