Document Detail

Coronary thrombolytic therapy: state of the art.
MedLine Citation:
PMID:  3521234     Owner:  NLM     Status:  MEDLINE    
Ischemic heart disease remains a significant cause of morbidity and mortality in the United States. Thrombolytic therapy has given physicians the capability of limiting the amount of myocardial damage that occurs when there is an acute coronary artery thrombosis and resulting myocardial infarction. This review summarizes current concepts about action mechanisms of the major thrombolytic agents, the technique and clinical results of intracoronary thrombolytic therapy, intravenous vs intracoronary administration, postthrombolytic management of underlying coronary artery disease, new agents being developed, and directions for future investigations.
M Marx; D C Levin
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  AJR. American journal of roentgenology     Volume:  147     ISSN:  0361-803X     ISO Abbreviation:  AJR Am J Roentgenol     Publication Date:  1986 Jul 
Date Detail:
Created Date:  1986-07-14     Completed Date:  1986-07-14     Revised Date:  2008-02-15    
Medline Journal Info:
Nlm Unique ID:  7708173     Medline TA:  AJR Am J Roentgenol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1-8     Citation Subset:  AIM; IM    
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MeSH Terms
Coronary Circulation / drug effects
Coronary Disease / drug therapy*,  mortality
Fibrinolytic Agents / administration & dosage,  adverse effects,  therapeutic use*
Heart Ventricles / drug effects
Infusions, Intra-Arterial
Infusions, Parenteral
Myocardial Infarction / drug therapy*
Postoperative Complications / surgery
Streptokinase / administration & dosage,  adverse effects,  pharmacology,  therapeutic use*
Reg. No./Substance:
0/Fibrinolytic Agents; EC 3.4.-/Streptokinase

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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