Document Detail


Coronary sclerosis risk factors in males with special reference to lipoproteins and apoproteins: establishing an index.
MedLine Citation:
PMID:  2283305     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
In order to ascertain the most effective index for predicting coronary sclerosis, the concentration of lipids, lipoproteins, and apoproteins in serum were determined in 45 males aged over 44 with angiographically diagnosed effort angina and in 153 male controls aged over 44 without ischemic heart disease (IHD) on physical examination. The results of our study are summarized as follows. 1) Alcohol intake of 25 g/day or more and smoking of 20 cigarettes/day or more showed significant odds ratios of 0.47 and 2.33, respectively. 2) By decrease of 10 mg/dl in HDLC level or of 10 mg/dl in Apo-AI level, the possibility of coronary sclerosis increases twofold after adjusting the effects of confounders. 3) LDLC/HDLC and Apo-B/Apo-AI are effective indices for predicting coronary sclerosis and, in particular, the probability of coronary sclerosis increases 3.8 times by increase of 0.5 in Apo-B/Apo-AI.
Authors:
M Kawanishi; A Nakamoto; G Konemori; I Horiuchi; G Kajiyama
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Hiroshima journal of medical sciences     Volume:  39     ISSN:  0018-2052     ISO Abbreviation:  Hiroshima J. Med. Sci.     Publication Date:  1990 Sep 
Date Detail:
Created Date:  1991-03-18     Completed Date:  1991-03-18     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0421060     Medline TA:  Hiroshima J Med Sci     Country:  JAPAN    
Other Details:
Languages:  eng     Pagination:  61-4     Citation Subset:  IM    
Affiliation:
Department of Biometrics, Hiroshima University, Japan.
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MeSH Terms
Descriptor/Qualifier:
Aged
Apolipoproteins A / blood
Apolipoproteins B / blood
Apolipoproteins C / blood
Apolipoproteins E / blood
Cholesterol / blood
Cholesterol, HDL / blood
Cholesterol, LDL / blood
Coronary Artery Disease / epidemiology*,  metabolism
Ethanol / adverse effects
Humans
Male
Middle Aged
Odds Ratio
Risk Factors
Smoking / adverse effects
Triglycerides / blood
Chemical
Reg. No./Substance:
0/Apolipoproteins A; 0/Apolipoproteins B; 0/Apolipoproteins C; 0/Apolipoproteins E; 0/Cholesterol, HDL; 0/Cholesterol, LDL; 0/Triglycerides; 57-88-5/Cholesterol; 64-17-5/Ethanol

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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