| Coronary pressure measurement after stenting predicts adverse events at follow-up: a multicenter registry. | |
| | |
MedLine Citation:
|
PMID: 12081986 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
BACKGROUND: Coronary stenting is associated with a restenosis rate of 15% to 20% at 6-month follow-up, despite optimum angiographic stent implantation. In this multicenter registry, we investigated the relation between optimum physiological stent implantation as assessed by poststent fractional flow reserve (FFR) and outcome at 6 months. METHODS AND RESULTS: In 750 patients, coronary pressure measurement at maximum hyperemia was performed after angiographically apparently satisfactory stent implantation. Poststenting FFR was calculated and related to major adverse events (including need for repeat target vessel revascularization) at 6 months. In 76 patients (10.2%), at least 1 adverse event occurred. Five patients died, 19 experienced myocardial infarction, and 52 underwent at least 1 repeat target vessel revascularization. By multivariate analysis, FFR immediately after stenting was the most significant independent variable related to all types of events. In 36% of the patients, FFR normalized (>0.95), and event rate was 4.9% in that group. In 32% of the patients, poststent FFR was between 0.90 and 0.95, and event rate was 6.2%. In 32% of patients, poststent FFR was <0.90, and event rate was 20.3%. In 6% of the patients, FFR was <0.80, and event rate was 29.5% (P<0.001). CONCLUSIONS: FFR after stenting is a strong independent predictor of outcome at 6 months. |
| | |
Authors:
|
Nico H J Pijls; Volker Klauss; Uwe Siebert; Eric Powers; Kenji Takazawa; William F Fearon; Javier Escaned; Yukio Tsurumi; Takashi Akasaka; Habib Samady; Bernard De Bruyne; |
Related Documents
:
|
10155116 - New challenges in coronary stenting. 19783056 - Long-term safety and efficacy of sirolimus- vs. paclitaxel-eluting stent implantation f... 9591896 - Clinical outcome at six months of coronary stenting followed by ticlopidine monotherapy. 3876006 - Expandable intrahepatic portacaval shunt stents: early experience in the dog. 18654006 - Impact of culprit plaque composition on the no-reflow phenomenon in patients with acute... 7553836 - Importance of a non-dominant right coronary artery occlusion presenting as sudden cardi... |
Publication Detail:
|
Type: Clinical Trial; Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't |
Journal Detail:
|
Title: Circulation Volume: 105 ISSN: 1524-4539 ISO Abbreviation: Circulation Publication Date: 2002 Jun |
Date Detail:
|
Created Date: 2002-06-25 Completed Date: 2002-07-08 Revised Date: 2006-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 0147763 Medline TA: Circulation Country: United States |
Other Details:
|
Languages: eng Pagination: 2950-4 Citation Subset: AIM; IM |
Affiliation:
|
Department of Cardiology, Catharina Hospital, Eindhoven, The Netherlands. cardiologie.catharina.zks@wxs.nl |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Blood Pressure Coronary Circulation* Coronary Restenosis / etiology, physiopathology* Follow-Up Studies Humans Middle Aged Registries Stents / adverse effects* Treatment Outcome |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Early resolution of ST-segment elevation correlates with myocardial salvage assessed by Tc-99m sesta...
Next Document: Omapatrilat reduces pulse pressure and proximal aortic stiffness in patients with systolic hypertens...