Document Detail

Coronary myogenic responses to abrupt changes in aortic blood pressure in anaesthetized dogs.
MedLine Citation:
PMID:  2245024     Owner:  NLM     Status:  MEDLINE    
A transient increase in coronary transmural pressure was produced in anaesthetized dogs by occlusion of the descending thoracic aorta. Aortic blood pressure (ABP), left ventricular pressure and coronary flow were measured; coronary vascular resistance (CVR) was calculated. Results were similar in innervated and denervated hearts. Occlusion for 10 and 20 s resulted in no change in CVR for 15 s, followed by a metabolic dilatation attributable to enhanced oxygen demand; after release the fall in ABP resulted in an immediate increase in CVR, caused by vascular elastic recoil, followed by hyperaemia.
M Dambrosio; D Gattullo; R J Linden; G Losano; P Pagliaro; P Vono
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Experimental physiology     Volume:  75     ISSN:  0958-0670     ISO Abbreviation:  Exp. Physiol.     Publication Date:  1990 Sep 
Date Detail:
Created Date:  1991-01-09     Completed Date:  1991-01-09     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  9002940     Medline TA:  Exp Physiol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  725-8     Citation Subset:  IM    
Istituto di Anestesiologia e Rianimazione, Università di Bari, Italy.
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MeSH Terms
Aorta / physiology*
Blood Pressure*
Coronary Circulation
Coronary Vessels / physiology*
Muscle, Smooth, Vascular / physiology*
Vascular Resistance

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