Document Detail

Coronary microcirculation during left heart bypass with a centrifugal pump.
MedLine Citation:
PMID:  8817976     Owner:  NLM     Status:  MEDLINE    
To estimate coronary microcirculation during left heart bypass (LHB), we performed an experimental comparison study of LHB and intraaortic balloon pumping (IABP). LHB was performed with a BioMedicus BP-80 pump supporting half of the flow of cardiac output whereas the IABP was pumped in a 1:1 mode for cardiogenic shock in a swine model. Coronary circulations were analyzed by electromagnetic flowmeter, pulsed Doppler velocimeter, and laser Doppler flowmeter. Left ventricular end-diastolic pressure (LVEDP) was reduced significantly by LHB. Although there was no significant difference in epicardial flow between the LHB and IABP groups, endo cardial flow was increased significantly by LHB. In the LHB group, the systolic reverse wave of the coronary velocity called a myocardial invalid circulation was reduced remarkably. There was a significant inverse correlation between endocardial flow and LVEDP. These results suggested that LHB was more effective for myocardial microcirculation than was IABP.
M Hata; M Shiono; Y Orime; K Nakata; A Sezai; H Yamada; T Saito; Y Sezai
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Artificial organs     Volume:  20     ISSN:  0160-564X     ISO Abbreviation:  Artif Organs     Publication Date:  1996 Jun 
Date Detail:
Created Date:  1996-12-11     Completed Date:  1996-12-11     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7802778     Medline TA:  Artif Organs     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  678-80     Citation Subset:  IM    
Second Department of Surgery, Nihon University School of Medicine, Tokyo, Japan.
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MeSH Terms
Blood Flow Velocity / physiology
Blood Pressure / physiology
Coronary Circulation / physiology*
Disease Models, Animal
Heart Bypass, Left / methods*
Heart-Assist Devices / standards*
Intra-Aortic Balloon Pumping / methods*
Laser-Doppler Flowmetry
Shock, Cardiogenic / therapy*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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