| Coronary microcirculation during left heart bypass with a centrifugal pump. | |
MedLine Citation:
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PMID: 8817976 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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To estimate coronary microcirculation during left heart bypass (LHB), we performed an experimental comparison study of LHB and intraaortic balloon pumping (IABP). LHB was performed with a BioMedicus BP-80 pump supporting half of the flow of cardiac output whereas the IABP was pumped in a 1:1 mode for cardiogenic shock in a swine model. Coronary circulations were analyzed by electromagnetic flowmeter, pulsed Doppler velocimeter, and laser Doppler flowmeter. Left ventricular end-diastolic pressure (LVEDP) was reduced significantly by LHB. Although there was no significant difference in epicardial flow between the LHB and IABP groups, endo cardial flow was increased significantly by LHB. In the LHB group, the systolic reverse wave of the coronary velocity called a myocardial invalid circulation was reduced remarkably. There was a significant inverse correlation between endocardial flow and LVEDP. These results suggested that LHB was more effective for myocardial microcirculation than was IABP. |
Authors:
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M Hata; M Shiono; Y Orime; K Nakata; A Sezai; H Yamada; T Saito; Y Sezai |
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Publication Detail:
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Type: Comparative Study; Journal Article |
Journal Detail:
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Title: Artificial organs Volume: 20 ISSN: 0160-564X ISO Abbreviation: Artif Organs Publication Date: 1996 Jun |
Date Detail:
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Created Date: 1996-12-11 Completed Date: 1996-12-11 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 7802778 Medline TA: Artif Organs Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 678-80 Citation Subset: IM |
Affiliation:
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Second Department of Surgery, Nihon University School of Medicine, Tokyo, Japan. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Animals Blood Flow Velocity / physiology Blood Pressure / physiology Centrifugation Coronary Circulation / physiology* Disease Models, Animal Heart Bypass, Left / methods* Heart-Assist Devices / standards* Intra-Aortic Balloon Pumping / methods* Laser-Doppler Flowmetry Shock, Cardiogenic / therapy* Swine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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