| Coronary intimal thickenings and lipids in Finnish children who died violently. | |
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MedLine Citation:
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PMID: 3867229 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Intimal thickenings of the coronary arteries were found in healthy children who died violently, of both sexes even in children under 5 years of age. The average incidence was 53 % of the 75 cases. Splitting of the internal elastic lamina was the primary finding, followed by local increase in smooth muscle cells. The thickening could occupy 50 % of the coronary lumen. The accumulation of esterified cholesterol in the coronary arteries began before the age of 10 years. The fatty acid composition of the cholesterol esters suggests that they are derived from the blood. The question whether the thickenings are precursors of forthcoming coronary atheromas needs further detailed studies, especially in young adults. |
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Authors:
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J Hirvonen; S Ylä-Herttuala; H Laaksonen; M Möttönen; T Nikkari; E Pesonen; J Raekallio; H K Akerblom |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Acta paediatrica Scandinavica. Supplement Volume: 318 ISSN: 0300-8843 ISO Abbreviation: Acta Paediatr Scand Suppl Publication Date: 1985 |
Date Detail:
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Created Date: 1986-03-11 Completed Date: 1986-03-11 Revised Date: 2008-02-20 |
Medline Journal Info:
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Nlm Unique ID: 0173166 Medline TA: Acta Paediatr Scand Suppl Country: SWEDEN |
Other Details:
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Languages: eng Pagination: 221-4 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Child Child, Preschool Cholesterol / blood Cholesterol Esters / blood Coronary Disease / blood, pathology* Coronary Vessels / pathology* Elastic Tissue / pathology Female Finland Humans Infant Infant, Newborn Lipids / blood* Male Muscle, Smooth, Vascular / pathology Phospholipids / blood Pregnancy Prospective Studies |
| Chemical | |
Reg. No./Substance:
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0/Cholesterol Esters; 0/Lipids; 0/Phospholipids; 57-88-5/Cholesterol |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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