Document Detail


Coronary heart disease and upper airway obstruction.
MedLine Citation:
PMID:  10607199     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Coronary heart disease (CHD) is a leading cause of death among middle-aged men. In the same age group the spectrum of upper airway obstruction from habitual snoring to obstructive sleep apnoea syndrome (OSAS) is frequent. In several studies snoring was found to be an important risk factor for ischaemic heart disease. The prevalence of OSAS in patients with CHD, profile of risk factors and ventricular arrhythmias was determined in a prospective manner in 78 patients with stenosis of one or more coronary arteries at coronary arterography. OSAS was found in 27 patients (34.6%). Mean respiratory disturbance index (RDI) was 23.9. RDI increased with higher age. No significant differences in both groups could be found in ventricular arrhythmias, left ventricular ejection fraction and risk factors, except hyperuricaemia and adiposity. OSAS is frequent in patients with CHD and may be an additional risk factor besides the known coronary risk factors. Patients with the combination of CHD and OSAS have to be regarded as a group at particular risk because of several interactions between OSAS and coronary haemodynamics. Furthermore the microstructure of sleep in patients with nocturnal myocardial ischaemia is disturbed.
Authors:
Schäfer; Köhler; Ploch; Peter
Related Documents :
1878609 - Burnout as a risk factor for coronary heart disease.
16679079 - Value of routine admission laboratory tests to predict thirty-day mortality in patients...
16762079 - Modular prevention of heart disease following acute coronary syndrome (acs) [isrctn4298...
19427679 - Prothrombin fragment 1 + 2 is associated with intima media thickness of the carotid art...
21652169 - Percutaneous closure of postinfarction ventricular septal defect: cardiac magnetic reso...
22559109 - Mitral valve repair under cardiopulmonary bypass in small-breed dogs: 48 cases (2006-20...
2684459 - Prediction of arrhythmic events in patients following myocardial infarction.
19118249 - Cardiovascular death and nonfatal myocardial infarction in acute coronary syndrome pati...
2551529 - One hour of myocardial ischemia decreases the activity of the stimulatory guanine-nucle...
Publication Detail:
Type:  JOURNAL ARTICLE    
Journal Detail:
Title:  Journal of sleep research     Volume:  4     ISSN:  1365-2869     ISO Abbreviation:  J Sleep Res     Publication Date:  1995 Jun 
Date Detail:
Created Date:  1999-12-21     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9214441     Medline TA:  J Sleep Res     Country:  -    
Other Details:
Languages:  ENG     Pagination:  185-189     Citation Subset:  -    
Affiliation:
Department of Medicine, Cardiology and Respiratory Medicine, University of Bonn, Bonn.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Pulmonary artery pressure in sleep apnoea and snoring.
Next Document:  Clinical significance of ventricular late potentials in patients with obstructive sleep apnoea.