Document Detail

Coronary heart disease events preventable by control of blood pressure and lipids in US adults with hypertension.
MedLine Citation:
PMID:  17541329     Owner:  NLM     Status:  MEDLINE    
Hypertension (HTN) and dyslipidemia are major risk factors for coronary heart disease (CHD). In 676 (projected to 26.1 million) US persons from the National Health and Nutrition Examination Survey (NHANES) 2001-2002 with HTN, the authors estimated the preventable CHD events from statistical control of blood pressure (BP) and lipid levels. Using Framingham algorithms, the authors projected the CHD events that could be prevented from statistical control of BP, low-density lipoprotein cholesterol, and high-density lipoprotein cholesterol. If BP was controlled to nominal levels, the authors projected 19% of CHD events (37% if controlled to optimal) would be prevented. Improving lipid levels to nominal levels was estimated to prevent 27% of CHD events (62% if controlled to optimal). Combined control of BP and lipid levels to nominal levels was projected to prevent 38% of CHD events (76% if controlled to optimal). The authors' results demonstrate that combined control of BP and lipid levels may prevent the majority of CHD events in Americans with HTN.
Victor A Lopez; Stanley S Franklin; Simon Tang; Nathan D Wong
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of clinical hypertension (Greenwich, Conn.)     Volume:  9     ISSN:  1524-6175     ISO Abbreviation:  J Clin Hypertens (Greenwich)     Publication Date:  2007 Jun 
Date Detail:
Created Date:  2007-06-01     Completed Date:  2007-07-12     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100888554     Medline TA:  J Clin Hypertens (Greenwich)     Country:  United States    
Other Details:
Languages:  eng     Pagination:  436-43     Citation Subset:  IM    
Heart Disease Prevention Program, Division of Cardiology, Department of Medicine, University of California, Irvine, CA 92697, USA.
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MeSH Terms
Blood Pressure / drug effects*,  physiology
Cholesterol, HDL / blood
Cholesterol, LDL / blood
Coronary Disease / etiology,  physiopathology,  prevention & control*
Dyslipidemias / blood,  complications,  drug therapy*
Hypertension / complications,  drug therapy*
Middle Aged
Nutrition Surveys
Risk Factors
United States
Reg. No./Substance:
0/Cholesterol, HDL; 0/Cholesterol, LDL

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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