| Coronary heart disease events preventable by control of blood pressure and lipids in US adults with hypertension. | |
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MedLine Citation:
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PMID: 17541329 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Hypertension (HTN) and dyslipidemia are major risk factors for coronary heart disease (CHD). In 676 (projected to 26.1 million) US persons from the National Health and Nutrition Examination Survey (NHANES) 2001-2002 with HTN, the authors estimated the preventable CHD events from statistical control of blood pressure (BP) and lipid levels. Using Framingham algorithms, the authors projected the CHD events that could be prevented from statistical control of BP, low-density lipoprotein cholesterol, and high-density lipoprotein cholesterol. If BP was controlled to nominal levels, the authors projected 19% of CHD events (37% if controlled to optimal) would be prevented. Improving lipid levels to nominal levels was estimated to prevent 27% of CHD events (62% if controlled to optimal). Combined control of BP and lipid levels to nominal levels was projected to prevent 38% of CHD events (76% if controlled to optimal). The authors' results demonstrate that combined control of BP and lipid levels may prevent the majority of CHD events in Americans with HTN. |
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Authors:
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Victor A Lopez; Stanley S Franklin; Simon Tang; Nathan D Wong |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Journal of clinical hypertension (Greenwich, Conn.) Volume: 9 ISSN: 1524-6175 ISO Abbreviation: J Clin Hypertens (Greenwich) Publication Date: 2007 Jun |
Date Detail:
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Created Date: 2007-06-01 Completed Date: 2007-07-12 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 100888554 Medline TA: J Clin Hypertens (Greenwich) Country: United States |
Other Details:
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Languages: eng Pagination: 436-43 Citation Subset: IM |
Affiliation:
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Heart Disease Prevention Program, Division of Cardiology, Department of Medicine, University of California, Irvine, CA 92697, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Algorithms Blood Pressure / drug effects*, physiology Cholesterol, HDL / blood Cholesterol, LDL / blood Coronary Disease / etiology, physiopathology, prevention & control* Dyslipidemias / blood, complications, drug therapy* Female Forecasting Humans Hypertension / complications, drug therapy* Male Middle Aged Nutrition Surveys Risk Factors United States |
| Chemical | |
Reg. No./Substance:
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0/Cholesterol, HDL; 0/Cholesterol, LDL |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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