Document Detail

Coronary heart disease attack rate, incidence and mortality 1975-1994 in Göteborg, Sweden.
MedLine Citation:
PMID:  9129885     Owner:  NLM     Status:  MEDLINE    
MATERIAL AND METHODS: Data from the Göteborg myocardial infarction register were used to investigate trends in attack rate, incidence of non-fatal myocardial infarction and mortality from coronary heart disease in persons aged 64 and below during the period 1975-1994. RESULTS: Myocardial infarction was defined according to strict criteria which remained the same throughout the study period. Attack rate and incidence were 3-5 times higher among men than women. The ratio of recurrent infarcts out of all attacks increased with increasing age and was 14%, 20% and 24% for men aged 35-44, 45-54, and 55-64, respectively. Corresponding rates for women were 8%, 14%, and 22%, respectively. Both attack rate and incidence decreased significantly by 2.1-3.9% per year during the study period for most age groups. The 28-day fatality rate (hospitalized as well as non-hospitalized cases) tended to decline, but significantly so only in the oldest men. The same was true for 28-day fatality among hospitalized patients. The majority of all coronary heart disease deaths occurred outside hospital in people unaware they had coronary heart disease. Mortality from coronary heart disease decreased by 2.0-6.8% per year during the study period. In-hospital treatment of myocardial infarction with intravenous beta-blockers followed by oral treatment, nitroglycerin and thrombolytics increased during the study period. Coronary surgery and angioplasty were used in less than 5% of patients during the study period, but increased substantially in 1994. CONCLUSION: Coronary heart disease and mortality in ages below 65 years are now decreasing in Sweden. Decreasing short-term mortality is almost certainly due to more efficient treatment in hospital, but as the majority of coronary heart disease deaths occur outside hospital and in people unaware they have coronary heart disease, primary prevention is still very important.
L Wilhelmsen; A Rosengren; S Johansson; G Lappas
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  European heart journal     Volume:  18     ISSN:  0195-668X     ISO Abbreviation:  Eur. Heart J.     Publication Date:  1997 Apr 
Date Detail:
Created Date:  1997-07-17     Completed Date:  1997-07-17     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8006263     Medline TA:  Eur Heart J     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  572-81     Citation Subset:  IM    
Department of Medicine, Ostra University Hospital, Göteborg University, Sweden.
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MeSH Terms
Cause of Death
Coronary Disease / mortality*,  therapy
Cross-Sectional Studies
Death, Sudden, Cardiac / epidemiology,  prevention & control
Middle Aged
Myocardial Infarction / mortality*,  therapy
Registries / statistics & numerical data
Survival Analysis
Sweden / epidemiology
Treatment Outcome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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