Document Detail

Coronary heart disease after mediastinal irradiation for Hodgkin's disease.
MedLine Citation:
PMID:  1251845     Owner:  NLM     Status:  MEDLINE    
Attention is called to the development of coronary heart disease in two patients several years after they received mediastinal irradiation for Hodgkin's disease. One patient, a 33 year old man, died suddenly eight years after irradiation; necropsy disclosed marked narrowing of all three major coronary arteries. In addition to severe intima fibrous thickening, there also was considerable adventitial scarring of the coronary arteries. This type of coronary sclerosis is different from that seen in the usual patient with coronary heart disease. The second patient, a 42 year old man, had an acute myocardial infarction on two occasions, the first six years after mediastinal irradiation. Observations in previously described patients with coronary heart disease almost surely induced by therapeutic irradiation for Hodgkin's disease are reviewed.
R A McReynolds; G L Gold; W C Roberts
Related Documents :
24814645 - Viscoelastic properties of normal and infarcted myocardium measured by a multifrequency...
10555435 - Corneal arcus: indicator for severity of coronary atherosclerosis?
23990185 - Evaluation of the effect of mitral stenosis severity on the left ventricular systolic f...
24959555 - Assessment of myocardial contractile function using global and segmental circumferentia...
1512335 - Functional recovery after coronary revascularization for chronic coronary artery diseas...
18549845 - Usefulness of adiponectin to predict myocardial salvage following successful reperfusio...
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  The American journal of medicine     Volume:  60     ISSN:  0002-9343     ISO Abbreviation:  Am. J. Med.     Publication Date:  1976 Jan 
Date Detail:
Created Date:  1976-04-23     Completed Date:  1976-04-23     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0267200     Medline TA:  Am J Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  39-45     Citation Subset:  AIM; IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Coronary Disease / etiology*,  pathology
Coronary Vessels / radiation effects
Hodgkin Disease / radiotherapy*
Mediastinal Neoplasms / radiotherapy*
Radiation Injuries / etiology*
Radiotherapy / adverse effects*
Radiotherapy Dosage
Time Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  A new familial syndrome characterized by pigmentary retinopathy, hypogonadism, mental retardation, n...
Next Document:  The clinical spectrum of ascites associated with maintenance dialysis.